Dementia is a frequent problem encountered in advanced stages of Parkinson disease (PD).
In recent years, research has focused on the pre-dementia stages of cognitive impairment in …

Immune processes have a vital role in CNS homeostasis, resilience and brain reserve. Our
cognitive and social abilities rely on a highly sensitive and fine-tuned equilibrium of immune …

Common risk factors for psychiatric and other brain disorders are likely to converge on
biological pathways influencing the development and maintenance of brain structure and …

Nearly all human complex traits and disease phenotypes exhibit some degree of sex
differences, including differences in prevalence, age of onset, severity or disease …

Complex interactions between the immune system and the brain might have important
aetiological and therapeutic implications for neuropsychiatric brain disorders. A possible …

Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system and
common cause of non-traumatic neurological disability in young adults. The likelihood for an …

In 2007, the clinical and research profile of illusions, hallucinations, delusions and related
symptoms in Parkinson disease (PD) was raised with the publication of a consensus …

Schizophrenia is a severe psychiatric disorder with considerable morbidity and mortality.
Although the past two decades have seen limited improvement in the treatment of …

Importance Recent genome-wide association studies (GWAS) and pathway analyses
supported long-standing observations of an association between immune-mediated …

Major mental diseases such as autism, bipolar disorder, schizophrenia, and major
depressive disorder are debilitating illnesses with complex etiologies. Recent findings show …