Although many details remain still elusive, it became increasingly evident in recent years
that mechanosensing of microenvironmental biophysical cues and subsequent …

First-line treatments for post-traumatic stress disorder (PTSD) encompass a wide range of
pharmacotherapies and psychotherapies. However, many patients fail to respond to such …

The current methods of generating human cerebral organoids rely excessively on the use of
Matrigel or other external extracellular matrices (ECM) for cell micro-environmental …

Tissue engineering is a research domain that deals with the growth of various kinds of
tissues with the help of synthetic composites. With the culmination of nanotechnology and …

Astrocytes' organisation affects the functioning and the fine morphology of the brain, both in
physiological and pathological contexts. Although many aspects of their role have been …

Mechanosensing, the ability of cells to perceive and interpret the microenvironmental
biophysical cues (such as the nanotopography), impacts strongly cellular behaviour through …

The ability to control adhesion and the spatial organization of cells over nanoscale surfaces
is essential in tissue engineering, regenerative medicine, the growth of organoids and …

Nanostructured zirconia and gold films (ns-Au/ZrOx) have been demonstrated as devices
characterized by non-linear and hysteretic electrical behavior, with short-term memory and …

Neurons in the central nervous system communicate with each other by activating billions of
tiny synaptic boutons distributed along their fine axons. These presynaptic varicosities are …

Chemical synapses are tiny and overcrowded environments, deeply embedded inside brain
tissue and enriched with thousands of protein species. Many efforts have been devoted to …