Significance: Hydrogen sulfide (H2S), an important regulator of physiology and health, helps
resolve inflammation and promotes tissue repair in the gastrointestinal tract. Recent …

For decades, the major focus of redox biology has been oxygen, the most abundant element
on Earth. Molecular oxygen functions as the final electron acceptor in the mitochondrial …

Emergent resistance to all clinical antibiotics calls for the next generation of therapeutics.
Here we report an effective antimicrobial strategy targeting the bacterial hydrogen sulfide …

Subcellular compartments often serve to store nutrients or sequester labile or toxic
compounds. As bacteria mostly do not possess membrane-bound organelles, they often …

The infected host deploys generalized oxidative stress caused by small inorganic reactive
molecules as antibacterial weapons. An emerging consensus is that hydrogen sulfide (H 2 …

Acinetobacter infections have high rates of mortality due to an increasing incidence of
infections by multidrug-resistant (MDR) and extensively-drug-resistant (XDR) strains …

Abstract L-Ergothioneine (ET), the 2-thioimidazole derivative of trimethylhistidine, is
biosynthesized by select fungi and bacteria, notably Mycobacterium tuberculosis, and …

Bacterial pathogens that cause invasive disease in the vertebrate host must adapt to host
efforts to cripple their viability. Major host insults are reactive oxygen and reactive nitrogen …

Background Acinetobacter baumannii is an important pathogen in clinical infections, and
biofilm formation is an effective way for A. baumannii to survive under external pressures. In …

Cysteine thiol-based transcriptional regulators orchestrate the coordinated regulation of
redox homeostasis and other cellular processes by 'sensing'or detecting a specific redox …