Outer membrane lipoprotein biogenesis: Lol is not the end

A Konovalova, TJ Silhavy - Philosophical Transactions of …, 2015 - royalsocietypublishing.org
Bacterial lipoproteins are lipid-anchored proteins that contain acyl groups covalently
attached to the N-terminal cysteine residue of the mature protein. Lipoproteins are …

[HTML][HTML] Identification of a novel plasmid-mediated colistin-resistance gene, mcr-2, in Escherichia coli, Belgium, June 2016

BB Xavier, C Lammens, R Ruhal… - …, 2016 - eurosurveillance.org
We identified a novel plasmid-mediated colistin-resistance gene in porcine and bovine
colistin-resistant Escherichia coli that did not contain mcr-1. The gene, termed mcr-2, a 1,617 …

Lipoproteins in Gram-negative bacteria: new insights into their biogenesis, subcellular targeting and functional roles

J El Rayes, R Rodríguez-Alonso, JF Collet - Current opinion in …, 2021 - Elsevier
Bacterial lipoproteins are globular proteins anchored to a membrane by a lipid moiety. By
discovering new functions carried out by lipoproteins, recent research has highlighted the …

[HTML][HTML] Detecting envelope stress by monitoring β-barrel assembly

SH Cho, J Szewczyk, C Pesavento, M Zietek… - Cell, 2014 - cell.com
The cell envelope protects bacteria from their surroundings. Defects in its integrity or
assembly are sensed by signal transduction systems, allowing cells to rapidly adjust. The …

PEGylation of the peptide Bac7 (1–35) reduces renal clearance while retaining antibacterial activity and bacterial cell penetration capacity

M Benincasa, S Zahariev, C Pelillo, A Milan… - European journal of …, 2015 - Elsevier
The proline-rich antibacterial peptide Bac7 (1–35) protects mice against Salmonella
typhimurium infection, despite its rapid clearance. To overcome this problem the peptide …

Agrobacterium tumefaciens Small Lipoprotein Atu8019 Is Involved in Selective Outer Membrane Vesicle (OMV) Docking to Bacterial Cells

LR Knoke, S Abad Herrera, K Götz… - Frontiers in …, 2020 - frontiersin.org
Outer membrane vesicles (OMVs), released from Gram-negative bacteria, have been
attributed to intra-and interspecies communication and pathogenicity in diverse bacteria …

Specific phenotypic, genomic, and fitness evolutionary trajectories toward streptomycin resistance induced by pesticide co-stressors in Escherichia coli

Y Xing, X Kang, S Zhang, Y Men - ISME communications, 2021 - academic.oup.com
To explore how co-occurring non-antibiotic environmental stressors affect evolutionary
trajectories toward antibiotic resistance, we exposed susceptible Escherichia coli K-12 …

Effect of size and N-terminal residue characteristics on bacterial cell penetration and antibacterial activity of the proline-rich peptide Bac7

F Guida, M Benincasa, S Zahariev… - Journal of medicinal …, 2015 - ACS Publications
Bac7 is a proline-rich antimicrobial peptide, selective for Gram-negative bacteria, which acts
intracellularly after membrane translocation. Progressively shortened fragments of Bac7 …

Some Gram-negative lipoproteins keep their surface topology when transplanted from one species to another and deliver foreign polypeptides to the bacterial surface

L Fantappie, C Irene, M De Santis, A Armini… - Molecular & Cellular …, 2017 - ASBMB
In Gram-negative bacteria, outer membrane-associated lipoproteins can either face the
periplasm or protrude out of the bacterial surface. The mechanisms involved in lipoprotein …

The journey of lipoproteins through the cell: one birthplace, multiple destinations

J Szewczyk, JF Collet - Advances in Microbial Physiology, 2016 - Elsevier
Bacterial lipoproteins are a very diverse group of proteins characterized by the presence of
an N-terminal lipid moiety that serves as a membrane anchor. Lipoproteins have a wide …