Biological properties of extracellular vesicles and their physiological functions
In the past decade, extracellular vesicles (EVs) have been recognized as potent vehicles of
intercellular communication, both in prokaryotes and eukaryotes. This is due to their capacity …
intercellular communication, both in prokaryotes and eukaryotes. This is due to their capacity …
Exosome-derived microRNAs of human milk and their effects on infant health and development
BC Melnik, W Stremmel, R Weiskirchen, SM John… - Biomolecules, 2021 - mdpi.com
Multiple biologically active components of human milk support infant growth, health and
development. Milk provides a wide spectrum of mammary epithelial cell-derived …
development. Milk provides a wide spectrum of mammary epithelial cell-derived …
Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the …
C Théry, KW Witwer, E Aikawa… - Journal of …, 2018 - Wiley Online Library
The last decade has seen a sharp increase in the number of scientific publications
describing physiological and pathological functions of extracellular vesicles (EVs), a …
describing physiological and pathological functions of extracellular vesicles (EVs), a …
Standardization of sample collection, isolation and analysis methods in extracellular vesicle research
The emergence of publications on extracellular RNA (exRNA) and extracellular vesicles
(EV) has highlighted the potential of these molecules and vehicles as biomarkers of disease …
(EV) has highlighted the potential of these molecules and vehicles as biomarkers of disease …
MicroRNA-containing T-regulatory-cell-derived exosomes suppress pathogenic T helper 1 cells
IS Okoye, SM Coomes, VS Pelly, S Czieso… - Immunity, 2014 - cell.com
Summary Foxp3+ T regulatory (Treg) cells prevent inflammatory disease but the mechanistic
basis of suppression is not understood completely. Gene silencing by RNA interference can …
basis of suppression is not understood completely. Gene silencing by RNA interference can …
Emerging role of extracellular vesicles in inflammatory diseases
The discovery that submicron-sized extracellular vesicles (EVs) are generated by both
prokaryotic and eukaryotic cells might have a profound effect on experimental and clinical …
prokaryotic and eukaryotic cells might have a profound effect on experimental and clinical …
Grape exosome-like nanoparticles induce intestinal stem cells and protect mice from DSS-induced colitis
Food-derived exosome-like nanoparticles pass through the intestinal tract throughout our
lives, but little is known about their impact or function. Here, as a proof of concept, we show …
lives, but little is known about their impact or function. Here, as a proof of concept, we show …
Treatment of brain inflammatory diseases by delivering exosome encapsulated anti-inflammatory drugs from the nasal region to the brain
In this study, exosomes used to encapsulate curcumin (Exo-cur) or a signal transducer and
activator of transcription 3 (Stat3) inhibitor, ie, JSI124 (Exo-JSI124) were delivered …
activator of transcription 3 (Stat3) inhibitor, ie, JSI124 (Exo-JSI124) were delivered …
Membrane vesicles as conveyors of immune responses
C Théry, M Ostrowski, E Segura - Nature reviews immunology, 2009 - nature.com
In multicellular organisms, communication between cells mainly involves the secretion of
proteins that then bind to receptors on neighbouring cells. But another mode of intercellular …
proteins that then bind to receptors on neighbouring cells. But another mode of intercellular …
Cancer exosomes trigger fibroblast to myofibroblast differentiation
There is a growing interest in the cell–cell communication roles in cancer mediated by
secreted vesicles termed exosomes. In this study, we examined whether exosomes …
secreted vesicles termed exosomes. In this study, we examined whether exosomes …