The benefits of exercise on health and longevity are well-established, and evidence
suggests that these effects are partially driven by a spectrum of bioactive molecules …

Extracellular vesicles originate from diverse subcellular compartments and are released in
the extracellular space. By transferring their cargoes into target cells and tissues, they now …

Cells secrete extracellular vesicles (EVs) by default and in response to diverse stimuli for the
purpose of cell communication and tissue homeostasis. EVs are present in all body fluids …

Endothelial microparticles (EMP) are released from activated or apoptotic endothelial cells
(EC s) and can be taken up by adjacent EC s, but their effect on vascular inflammation after …

Background Short-term exercise training programs that consist of moderate intensity
endurance training or high intensity interval training have become popular choices for …

Irisin is a PGC-1α-dependent myokine that causes increased energy expenditure by driving
the development of white adipose tissue into brown fat-like tissue. Exercise can improve …

Background. Exercise intensity can influence functional recovery after stroke, but the
mechanisms remain poorly understood. Objective. In chronic stroke, an intensity-dependent …

Interest in cell-derived microvesicles (or microparticles) within cardiovascular diagnostics
and therapeutics is rapidly growing. Microvesicles are often measured in the circulation at a …

Cognitive performance is usually impaired in those with serious mental illness (SMI).
Exercise may improve cognitive functioning, but studies examining the effects of exercise in …

The effect of endurance exercise on circulating microvesicle dynamics and their impact on
surrounding endothelial cells is unclear. Here we tested the hypothesis that exercise …