A major rise in the prevalence and impact of Alzheimer's disease (AD) is projected in the
coming decades, resulting from increasing life expectancy, thus leading to substantially …

Research progress on microRNAs as molecular markers in pancreatic cancer: a narrative
review - PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI Homepage …

In Systems Biology, the complex relationships between different entities in the cells are
modeled and analyzed using networks. Towards this aim, a rich variety of gene regulatory …

Background Pancreatic cancer (PC) remains one of the most lethal cancers. In contrast to
the steady increase in survival for most cancers, the 5-year survival remains low for PC …

Single-cell sequencing technologies offer a platform to explore deeper the complex
diseases and biological processes. On parallel, Systems Biology approaches can tackle part …

It has already been established by the systems-level approaches that the future of predictive
disease biomarkers will not be sketched by plain lists of genes or proteins or other biological …

In the last two decades, the medical sciences have changed their approach to pathogenesis
as well as to the diagnosis and treatment of complex human diseases. The main reason for …

Abstract Motivation Neurodegenerative diseases (NDs), including amyotrophic lateral
sclerosis, Parkinson's disease, Alzheimer's disease, and Huntington's disease, occur as a …

In the era of Systems Biology and growing flow of omics experimental data from high
throughput techniques, experimentalists are in need of more precise pathway-based tools to …

Motivation In the last years, systems-level network-based approaches have gained ground
in the research field of systems biology. These approaches are based on the analysis of …