Molnupiravir and its antiviral activity against COVID-19

L Tian, Z Pang, M Li, F Lou, X An, S Zhu… - Frontiers in …, 2022 - frontiersin.org
The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) constitutes a major worldwide public health threat …

What remains unsolved in sub-african environmental exposure information disclosure: a review

AA Dagestani, L Qing, M Abou Houran - Journal of Risk and Financial …, 2022 - mdpi.com
Background: Africa comprises the bulk of struggling economies. However, Sub-Saharan
Africa is experiencing rapid industrialization and urbanization. Excessive resource use …

Population genomics of Escherichia coli in livestock-keeping households across a rapidly developing urban landscape

DM Muloi, BA Wee, DMH McClean, MJ Ward… - Nature …, 2022 - nature.com
Quantitative evidence for the risk of zoonoses and the spread of antimicrobial resistance
remains lacking. Here, as part of the UrbanZoo project, we sampled Escherichia coli from …

Infectious RNA: human immunodeficiency virus (HIV) biology, therapeutic intervention, and the quest for a vaccine

Y van Heuvel, S Schatz, JF Rosengarten, J Stitz - Toxins, 2022 - mdpi.com
Different mechanisms mediate the toxicity of RNA. Genomic retroviral mRNA hijacks infected
host cell factors to enable virus replication. The viral genomic RNA of the human …

[HTML][HTML] Emergence of epidemic diseases: Zoonoses and other origins

RA Weiss, N Sankaran - Faculty reviews, 2022 - ncbi.nlm.nih.gov
Infectious diseases emerge via many routes and may need to overcome stepwise
bottlenecks to burgeon into epidemics and pandemics. About 60% of human infections have …

West Nile virus spread in Europe: Phylogeographic pattern analysis and key drivers

L Lu, F Zhang, BB Oude Munnink, E Munger… - PLoS …, 2024 - journals.plos.org
Background West Nile virus (WNV) outbreaks in birds, humans, and livestock have occurred
in multiple areas in Europe and have had a significant impact on animal and human health …

SegVir: Reconstruction of complete segmented RNA viral genomes from metatranscriptomes

X Tang, J Shang, G Chen, KHK Chan… - … Biology and Evolution, 2024 - academic.oup.com
Segmented RNA viruses are a complex group of RNA viruses with multi-segment genomes.
Reconstructing complete segmented viruses is crucial for advancing our understanding of …

Dual host and pathogen RNA-seq analysis unravels chicken genes potentially involved in resistance to highly pathogenic avian influenza virus infection

A Perlas, J Argilaguet, K Bertran… - Frontiers in …, 2021 - frontiersin.org
Highly pathogenic avian influenza viruses (HPAIVs) cause severe systemic disease and
high mortality rates in chickens, leading to a huge economic impact in the poultry sector …

Low-density lipoprotein receptor–related protein 1 (LRP1) as an auxiliary host factor for RNA viruses

S Devignot, TW Sha, TR Burkard… - Life Science …, 2023 - life-science-alliance.org
Viruses with an RNA genome are often the cause of zoonotic infections. In order to identify
novel pro-viral host cell factors, we screened a haploid insertion–mutagenized mouse …

Low Density Lipoprotein Receptor-Related Protein 1 (LRP1) is a host factor for RNA viruses including SARS-CoV-2

S Devignot, TW Sha, T Burkard, P Schmerer… - bioRxiv, 2022 - biorxiv.org
Viruses with an RNA genome are the main causes of zoonotic infections. In order to identify
novel pro-viral host cell factors, we screened a haploid insertion-mutagenized mouse …