PIWI-interacting RNAs (piRNAs) are a class of small non-coding RNAs that associate with
proteins of the PIWI clade of the Argonaute family. First identified in animal germ line cells …

In animals, PIWI-interacting RNAs (piRNAs) of 21–35 nucleotides in length silence
transposable elements, regulate gene expression and fight viral infection. piRNAs guide …

Piwi interacting RNAs (piRNAs) constitute novel small non-coding RNA molecules of
approximately 24–31 nucleotides in length that often bind to members of the piwi protein …

Discoveries over the past decade portend a paradigm shift in molecular biology. Evidence
suggests that RNA is not only functional as a messenger between DNA and protein but also …

PIWI-interacting RNAs (piRNAs) are a distinct class of small non-coding RNAs that form the
piRNA-induced silencing complex (piRISC) in the germ line of many animal species. The …

Small RNAs of 20–30 nucleotides can target both chromatin and transcripts, and thereby
keep both the genome and the transcriptome under extensive surveillance. Recent progress …

Since the discovery in 1993 of the first small silencing RNA, a dizzying number of small RNA
classes have been identified, including microRNAs (miRNAs), small interfering RNAs …

The discovery of millions of PIWI-interacting RNAs revealed a fascinating and unanticipated
dimension of biology. The PIWI–piRNA pathway has been commonly perceived as germline …

Abstract Small RNAs associate with Argonaute proteins and serve as sequence-specific
guides to regulate messenger RNA stability, protein synthesis, chromatin organization and …

During the past decade, small non-coding RNAs have rapidly emerged as important
contributors to gene regulation. To carry out their biological functions, these small RNAs …