Medicinal plants in Brazil: Pharmacological studies, drug discovery, challenges and perspectives

RC Dutra, MM Campos, ARS Santos… - Pharmacological research, 2016 - Elsevier
This review article focuses on pre-clinical and clinical studies with some selected Brazilian
medicinal plants in different areas of interest, conducted by research groups in Brazil and …

Subtribe Hyptidinae (Lamiaceae): A promising source of bioactive metabolites

H Bridi, G de Carvalho Meirelles… - Journal of …, 2021 - Elsevier
Abstract Ethnopharmacological relevance The subtribe Hyptidinae contains approximately
400 accepted species distributed in 19 genera (Hyptis, Eriope, Condea, Cantinoa …

Gastroprotective mechanisms of the monoterpene 1, 8-cineole (eucalyptol)

GF Rocha Caldas, ARS Oliveira, AV Araújo… - PLoS …, 2015 - journals.plos.org
Recently, our research group identified and reported 1, 8-cineole (CIN), a monoterpene that
naturally occur in many aromatic plants, as one of the major constituent of the essential oil …

Antiulcer Activity and Potential Mechanism of Action of the Leaves of Spondias mombin L.

SA Brito, CLF de Almeida, TI de Santana… - Oxidative medicine …, 2018 - Wiley Online Library
Spondias mombin L. is used in folk medicine for the treatment of inflammation and
gastrointestinal diseases. Our study investigated the antiulcer activity of S. mombin ethanolic …

Chemical characterization, toxicology and mechanism of gastric antiulcer action of essential oil from Gallesia integrifolia (Spreng.) Harms in the in vitro and in vivo …

K Arunachalam, SO Balogun, E Pavan… - Biomedicine & …, 2017 - Elsevier
Gallesia integrifolia is a Brazilian Amazon tree whose bark decoction is popularly used to
treat peptic ulcer. The essential oil from the inner stem bark of G. integrifolia (EOGi) was …

Achillea millefolium Essential Oil Mitigates Peptic Ulcer in Rats through Nrf2/HO-1 Pathway

MK Alomair, LS Alabduladheem, MA Almajed… - Molecules, 2022 - mdpi.com
Extreme ethanol ingestion is associated with developing gastric ulcers. Achillea millefolium
(yarrow) is one of the most commonly used herbs with numerous proven pharmacological …

Modulatory effect of silymarin on nuclear factor-erythroid-2-related factor 2 regulated redox status, nuclear factor-κB mediated inflammation and apoptosis in …

WA Keshk, SM Zahran, MA Katary, DAE Ali - Chemico-biological …, 2017 - Elsevier
Non-steroidal anti-inflammatory drugs (NSAIDs) consumption has been commonly
associated with gastric mucosal lesions including gastric ulcer. Silymarin (SM) is a flavonoid …

[HTML][HTML] In vivo and in silico anti-inflammatory properties of the sesquiterpene valencene

LBR Dantas, IS Alcântara, CPS Júnior… - Biomedicine & …, 2022 - Elsevier
Valencene (VLN) is a sesquiterpene found in juices and essential oils of citrus species such
as Cyperus rotundus. Considering the evidence that this species has anti-inflammatory …

Effects of the Hyptis martiusii Benth. leaf essential oil and 1, 8-cineole (eucalyptol) on the central nervous system of mice

ÁB Monteiro, IRA de Menezes… - Food and Chemical …, 2019 - Elsevier
The aim of this study was to characterize the central effects of the Hyptis martiusii leaf
essential oil (OEHM) and 1, 8-cineole (eucalyptol) using behavioral animal models. Gas …

[HTML][HTML] Therapeutic strategies of Moringa oleifera Lam.(Moringaceae) for stomach and forestomach ulceration induced by HCl/EtOH in rat model

W Dalhoumi, F Guesmi, A Bouzidi, S Akermi… - Saudi Journal of …, 2022 - Elsevier
Abstract Background The drumstick tree Moringa oleifera Lam.(Moringaceae), distributed in
many parts of the world, is an important food plant with high nutritional value and used in …