The role of immunotherapy in hepatocellular carcinoma: a systematic review and pooled analysis of 2,402 patients

IA Ziogas, AP Evangeliou, D Giannis, MH Hayat… - The …, 2021 - academic.oup.com
Abstract Background Immune checkpoints inhibitors (ICIs) have emerged as a treatment
option for several malignancies. Nivolumab, pembrolizumab, nivolumab plus ipilimumab …

Programmed cell death protein-1 (PD-1)/programmed death-ligand-1 (PD-L1) axis in hepatocellular carcinoma: prognostic and therapeutic perspectives

T Mocan, Z Sparchez, R Craciun, CN Bora… - Clinical and …, 2019 - Springer
Hepatocellular carcinoma (HCC) is the most common primary neoplasia of the liver. There
have been tremendous efforts in the development of therapeutic strategies in the last …

[PDF][PDF] Pembrolizumab for metastatic hepatocellular carcinoma following live donor liver transplantation: The silver bullet?

A Rammohan, MS Reddy, M Farouk, J Vargese… - …, 2018 - Wiley Online Library
Pembrolizumab for metastatic hepatocellular carcinoma following live donor liver transplantation:
The silver bullet? Page 1 Pembrolizumab for Metastatic Hepatocellular Carcinoma Following …

Adverse events of concurrent immune checkpoint inhibitors and antiangiogenic agents: a systematic review

L Gao, X Yang, C Yi, H Zhu - Frontiers in pharmacology, 2019 - frontiersin.org
Background: Immune checkpoint blockade has revolutionized the treatment of multiple
malignancies. Currently, however, the effect is not universal, with objective response rates …

Anti-PD-1 combined sorafenib versus anti-PD-1 alone in the treatment of advanced hepatocellular cell carcinoma: a propensity score-matching study

SC Chen, YH Huang, MH Chen, YP Hung, RC Lee… - BMC cancer, 2022 - Springer
Background Vascular endothelial growth factor (VEGF) plays a role in the tumor
microenvironment. Sorafenib, which inhibits the VEGF pathway, has an immune-modulation …

Efficacy and safety of camrelizumab plus transarterial chemoembolization in intermediate to advanced hepatocellular carcinoma patients: A prospective, multi-center …

R You, Q Xu, Q Wang, Q Zhang, W Zhou, C Cao… - Frontiers in …, 2022 - frontiersin.org
Objective Camrelizumab is a newly developed program-death receptor one inhibitor; the
real-world evidence about its application in hepatocellular carcinoma (HCC) treatment is …

[HTML][HTML] Immunotherapy in older patients with hepatocellular carcinoma

N Lyu, JZ Yi, M Zhao - European Journal of Cancer, 2022 - Elsevier
Hepatocellular carcinoma (HCC) is one of the most common types of cancer globally and is
currently the third leading cause of cancer-related deaths. Recently, immunotherapy using …

Are antiangiogenics a good 'partner'for immunotherapy in ovarian cancer?

E Garcia-Martinez, A Redondo, JM Piulats… - Angiogenesis, 2020 - Springer
Ovarian cancer (OC) is associated with poor survival because there are a limited number of
effective therapies. Two processes key to OC progression, angiogenesis and immune …

Cabozantinib in the treatment of hepatocellular carcinoma

ML B Peters, RA Miksad - Future Oncology, 2017 - Taylor & Francis
Despite clinical studies with different mechanisms of action, no new systemic therapies were
approved for hepatocellular carcinoma (HCC) between sorafenib in 2007 and regorafenib in …

Impact of tumor burden on prognostic prediction for patients with terminal stage hepatocellular carcinoma: a nomogram study

CY Hsu, PH Liu, SY Ho, YH Huang, YH Lee, YY Chiou… - PloS one, 2017 - journals.plos.org
Background The recently proposed nomogram of Barcelona Clinic Liver Cancer (BCLC)
lacks predictive accuracy for patients with stage D hepatocellular carcinoma (HCC). Tumor …