Immuno-positron emission tomography (immunoPET) is a paradigm-shifting molecular
imaging modality combining the superior targeting specificity of monoclonal antibody (mAb) …

Inert and stable radiolabeling of monoclonal antibodies (mAb), antibody fragments, or
antibody mimetics with radiometals is a prerequisite for immuno-PET. While radiolabeling is …

Immuno-positron emission tomography (immunoPET) is a molecular imaging modality
combining the high sensitivity of PET with the specific targeting ability of monoclonal …

Purpose Multiple myeloma (MM) remains incurable and its diagnosis relies heavily on bone
marrow aspiration and biopsy. CD38 is a glycoprotein highly specific for MM. Antibody …

Given that plenty of clinical findings and reviews have already explained in detail on the
progression of CD38 in multiple myeloma and haematological system tumours, here we no …

Purpose Pancreatic cancer is a malignant tumor with a high degree of malignancy, strong
heterogeneity, and high lethality. Trop2 is a transmembrane glycoprotein associated with the …

Extracellular vesicles (EVs) are promising tools for drug delivery across different biological
barriers. Here, we evaluated the potential of EVs-mediated delivery of CD38 siRNA on the …

Monoclonal antibodies (mAbs) were initially considered as a possible “magic bullet” for in
vivo elimination of tumor cells. mAbs represented the first step: however, as they were …

Hepatocellular carcinoma (HCC) is the most common primary malignant tumor of the liver,
but early diagnosis and effective treatment are still difficult. With the development of …

The prevalence of positron emission tomography (PET) imaging has advanced biomedical
applications for its ultrahigh sensitivity, deep tissue penetration and quantitative visualization …