Aneurysmal subarachnoid hemorrhage (SAH) affects six to nine people per 100,000 per
year, has a 35% mortality, and leaves many with lasting disabilities, often related to cognitive …

Subarachnoid haemorrhage is an uncommon and severe subtype of stroke affecting
patients at a mean age of 55 years, leading to loss of many years of productive life. The …

External ventricular drains (EVDs) are commonly placed to monitor intracranial pressure and
manage acute hydrocephalus in patients with a variety of intracranial pathologies. The …

Intracranial pressure monitoring devices have become the standard of care for the
management of patients with pathologies associated with intracranial hypertension. Given …

BACKGROUND: Subcortical injury resulting from conventional surgical management of
intracranial hemorrhage may counteract the potential benefits of hematoma evacuation …

Pharmacological interventions have been tested experimentally and clinically to prevent
hydrocephalus and avoid the need for shunting beginning in the 1950s. Clinical trials of …

Spontaneous subarachnoid hemorrhage (SAH) affects people with a mean age of 55 years.
Although there are about 9/100 000 cases per year worldwide, the young age and high …

Objective Intraventricular hemorrhage (IVH) is a negative prognostic factor in intracerebral
hemorrhage (ICH) and is associated with permanent shunt dependency in a substantial …

Background and Purpose—We conducted a randomized, open-label, phase 1/2a, dose-
escalation study of intraventricular sustained-release nimodipine (EG-1962) to determine …

External ventricular drains and lumbar drains are commonly used to divert cerebrospinal
fluid and to measure cerebrospinal fluid pressure. Although commonly encountered in the …