Molecular, morphological, and physiological heterogeneity is the inherent property of cells
which governs differences in their response to external influence. Tumor cell metabolic …

This paper provides an overview of the current research in the field of optical techniques for
cervical neoplasia detection and covers a wide range of the existing and emerging …

Time-correlated single photon counting (TCSPC) was born 54 years ago, in 1960, when
Bollinger and Thomas published a paper on the 'Measurement of Time Dependence of …

Background: The clinical application of fluorescent contrast agents (fluorescein, indocyanine
green, and aminolevulinic acid) with intraoperative microscopy has led to advances in …

This paper presents the use and characterization of an electrically focus tunable lens to
perform axial scanning in a confocal microscope. Lateral and axial resolution are …

Optical metabolic imaging measures fluorescence intensity and lifetimes from metabolic
cofactors nicotinamide adenine dinucleotide (NADH) and flavin adenine dinucleotide (FAD) …

Advancements in optical imaging techniques have revolutionized the field of biomedical
research, allowing for the comprehensive characterization of tissues and their underlying …

Cervical cancer remains a leading cause of cancer death among women in low-and middle-
income countries. Globally, cervical cancer prevention programs are hampered by a lack of …

In microscopic imaging of biological tissues, particularly real-time visualization of neuronal
activities, rapid acquisition of volumetric images poses a prominent challenge. Typically, two …

In some applications of biomedical imaging, a linear mixture model can represent the
constitutive elements (end-members) and their contributions (abundances) per pixel of the …