The nocebo effect

L Colloca - Annual review of pharmacology and toxicology, 2024 - annualreviews.org
Adverse nocebo responses can cause harm to patients and interfere with treatment
adherence and effects in both clinic practice and clinical trials. Nocebo responses refer to …

Placebo effects in osteoarthritis: implications for treatment and drug development

T Neogi, L Colloca - Nature Reviews Rheumatology, 2023 - nature.com
Osteoarthritis (OA) is the most common form of arthritis worldwide, affecting~ 500 million
people, yet there are no effective treatments to halt its progression. Without any structure …

Growing placebo response in TMS treatment for depression: a meta-analysis of 27-year randomized sham-controlled trials

Y Xu, Y Zhang, D Zhao, Y Tian, TF Yuan - Nature mental health, 2023 - nature.com
This meta-analysis investigated placebo responses in repetitive transcranial magnetic
stimulation treatment for depression, an area with limited systematic analysis. The initial …

Harnessing the placebo effect to enhance emotion regulation effectiveness and choice

R Shafir, M Israel, L Colloca - Scientific Reports, 2023 - nature.com
The placebo effect demonstrates how positive expectancies shape the effectiveness of
various treatments. Across studies, placebo treatments are interventions (creams, pills, etc.) …

[HTML][HTML] The post-roe political landscape demands a morality of caution for Women's health

S Goodday, D Karlin, C Suver, S Friend - Journal of Medical Internet …, 2022 - jmir.org
The recent Supreme Court decision (ie, Dobbs v. Jackson Women's Health Organization),
revoking the constitutional right to abortion in the United States, has the potential to …

[HTML][HTML] Construction and validation of chronic pain prediction model after total knee arthroplasty

J Qian, X Wang - Pakistan Journal of Medical Sciences, 2024 - ncbi.nlm.nih.gov
Objective: To explore the risk factors of chronic pain after total knee arthroplasty (TKA) and to
establish and verify a prediction model. Methods: As a retrospective observational study …

Learning by observing: a systematic exploration of modulatory factors and the impact of observationally induced placebo and nocebo effects on treatment outcomes

H Klauß, A Kunkel, D Müßgens, J Haaker… - Frontiers in …, 2024 - frontiersin.org
Introduction Observational learning (OL) refers to learning through observing other people's
behavior. OL has been suggested as an effective and simple tool to evoke treatment …

A novel investigation of placebo analgesia through social communication in mice

SK Totsch, RE Sorge - Behavioural Brain Research, 2024 - Elsevier
Background and aims In rodents, placebo analgesia is often investigated through direct
conditioning of stimuli, but humans can experience placebo analgesia through expectation …

Baseline heart rate variability predicts placebo hypoalgesia in men, but not women

J Krecké, AM Dierolf, KM Rischer, F Anton… - Frontiers in Pain …, 2023 - frontiersin.org
Introduction Placebo hypoalgesic effects vary greatly across individuals, making them
challenging to control for in clinical trials and difficult to use in treatment. We investigated the …

Can placebo effects go wrong?

L Colloca - Placebo Effects in Sport and Exercise, 2023 - books.google.com
In its broadest sense, the nocebo effect is an unwanted, negative, or unpleasant outcome
resulting from the suggestion or belief that a harmful treatment has been received. In early …