Alzheimer's disease (AD) is a multifactorial neurodegenerative disorder, characterized by
the formation, aggregation and accumulation of amyloid beta, perturbed metal (copper, iron …

Abstract Ethnopharmacological relevance The genus Uncaria belongs to the family
Rubiaceae, which mainly distributed in tropical regions, such as Southeast Asia, Africa and …

Age-related inflammation is the predominant factor for neurodegenerative diseases like
Alzheimer's disease (AD). In the present study, we examined memory performance and …

Purpose Alzheimer's disease (AD) is a growing concern in the modern society. The current
drugs approved by FDA are not very promising. Rhynchophylline (RIN) is a major active …

Brusatol occurs as a characteristic bioactive principle of Brucea javanica (L.) Merr., a
traditional medicinal herb frequently employed to tackle cancer in China. This work …

Alzheimer's disease (AD) is a chronic neurodegenerative disease which contributes to
memory loss and cognitive decline in the elderly. Fucoidan, extracted from brown algae, is a …

Cognitive impairments and cholinergic dysfunctions have been well reported in old age
disorders including Alzheimer's disease (AD). d-galactose (D-gal) has been reported as a …

Background: Uncaria rhynchophylla (Miq.) Jacks (Rubinaceae), a common herbal medicine
known as Gou-teng in Chinese, is commonly used in Chinese medicine practice for the …

Beta-amyloid peptide (Aβ), a major protein component of senile plaques, has been
considered as a critical cause in the pathogenesis of Alzheimer's disease (AD). Modulation …

The progressive accumulation of amyloid-β (Aβ) in the form of senile plaques has been
recognized as a key causative factor leading to the cognitive deficits seen in Alzheimer's …