The role of vitamin D in autoimmune diseases: could sex make the difference?

ML Dupuis, MT Pagano, M Pierdominici… - Biology of sex …, 2021 - Springer
Over the last decades, a central role for vitamin D in immune modulation has been well
established. The active form of vitamin D, ie, 1, 25-dihydroxyvitamin D, through the …

Vitamin D in neurological diseases

D Plantone, G Primiano, C Manco, S Locci… - International journal of …, 2022 - mdpi.com
Vitamin D may have multiple effects on the nervous system and its deficiency can represent
a possible risk factor for the development of many neurological diseases. Recent studies are …

Vitamin D and immune regulation: antibacterial, antiviral, anti-inflammatory

EL Bishop, A Ismailova, S Dimeloe… - Journal of Bone and …, 2021 - academic.oup.com
Regulation of immune function continues to be one of the most well recognized extraskeletal
actions of vitamin D. This stemmed initially from the discovery that antigen presenting cells …

Vitamin D supplementation in multiple sclerosis: a critical analysis of potentials and threats

J Feige, T Moser, L Bieler, K Schwenker, L Hauer… - Nutrients, 2020 - mdpi.com
Multiple sclerosis (MS) is a chronic inflammatory demyelinating and neurodegenerative
disease of the central nervous system (CNS). In recent years, vitamin D has gained …

Full spectrum of vitamin D immunomodulation in multiple sclerosis: Mechanisms and therapeutic implications

M Galoppin, S Kari, S Soldati, A Pal… - Brain …, 2022 - academic.oup.com
Vitamin D deficiency has been associated with the risk of multiple sclerosis, disease activity
and progression. Results from in vitro experiments, animal models and analysis of human …

Vitamin D and neurodegenerative diseases

W Wang, Y Li, X Meng - Heliyon, 2023 - cell.com
Neurodegenerative diseases, featured by progressive loss of structure or function of
neurons, are considered incurable at present. Movement disorders like tremor and postural …

[HTML][HTML] Vitamins D2 and D3 have overlapping but different effects on the human immune system revealed through analysis of the blood transcriptome

LR Durrant, G Bucca, A Hesketh… - Frontiers in …, 2022 - frontiersin.org
Vitamin D is best known for its role in maintaining bone health and calcium homeostasis.
However, it also exerts a broad range of extra-skeletal effects on cellular physiology and on …

Sunlight exposure exerts immunomodulatory effects to reduce multiple sclerosis severity

P Ostkamp, A Salmen, B Pignolet… - Proceedings of the …, 2021 - National Acad Sciences
Multiple sclerosis (MS) disease risk is associated with reduced sun-exposure. This study
assessed the relationship between measures of sun exposure (vitamin D [vitD], latitude) and …

How does vitamin D affect immune cells crosstalk in autoimmune diseases?

D Gallo, D Baci, N Kustrimovic, N Lanzo… - International Journal of …, 2023 - mdpi.com
Vitamin D is a secosteroid hormone that is highly involved in bone health. Mounting
evidence revealed that, in addition to the regulation of mineral metabolism, vitamin D is …

Effects of vitamin D and body mass index on disease risk and relapse hazard in multiple sclerosis: a Mendelian randomization study

M Vandebergh, B Dubois, A Goris - Neurology: Neuroimmunology …, 2022 - AAN Enterprises
Background and Objectives Decreased vitamin D levels and obesity are associated with an
increased risk for multiple sclerosis (MS). However, whether they also affect the disease …