Clinical neurology and epidemiology of the major neurodegenerative diseases

MG Erkkinen, MO Kim… - Cold Spring Harbor …, 2018 - cshperspectives.cshlp.org
Neurodegenerative diseases are a common cause of morbidity and cognitive impairment in
older adults. Most clinicians who care for the elderly are not trained to diagnose these …

Frontotemporal dementia

NT Olney, S Spina, BL Miller - Neurologic clinics, 2017 - neurologic.theclinics.com
Frontotemporal dementia (FTD) has undergone numerous changes in nomenclature and
categorization schemes since it was first described by Pick in 1892. Presently, FTD …

[HTML][HTML] Lysosome dysfunction as a cause of neurodegenerative diseases: Lessons from frontotemporal dementia and amyotrophic lateral sclerosis

J Root, P Merino, A Nuckols, M Johnson… - Neurobiology of disease, 2021 - Elsevier
Frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) are fatal
neurodegenerative disorders that are thought to exist on a clinical and pathological …

Prevalence, characteristics, and survival of frontotemporal lobar degeneration syndromes

ITS Coyle-Gilchrist, KM Dick, K Patterson… - Neurology, 2016 - AAN Enterprises
Objectives: To estimate the lifetime risk, prevalence, incidence, and mortality of the principal
clinical syndromes associated with frontotemporal lobar degeneration (FTLD) using revised …

Typical and atypical pathology in primary progressive aphasia variants

EG Spinelli, ML Mandelli, ZA Miller… - Annals of …, 2017 - Wiley Online Library
Objective To characterize in vivo signatures of pathological diagnosis in a large cohort of
patients with primary progressive aphasia (PPA) variants defined by current diagnostic …

Research criteria for the behavioral variant of Alzheimer disease: a systematic review and meta-analysis

R Ossenkoppele, EH Singleton, C Groot… - JAMA …, 2022 - jamanetwork.com
Importance The behavioral variant of Alzheimer disease (bvAD) is characterized by early
and predominant behavioral deficits caused by AD pathology. This AD phenotype is …

Criteria for the diagnosis of corticobasal degeneration

MJ Armstrong, I Litvan, AE Lang, TH Bak, KP Bhatia… - Neurology, 2013 - AAN Enterprises
Current criteria for the clinical diagnosis of pathologically confirmed corticobasal
degeneration (CBD) no longer reflect the expanding understanding of this disease and its …

Clinicopathological correlations in behavioural variant frontotemporal dementia

DC Perry, JA Brown, KL Possin, S Datta, A Trujillo… - Brain, 2017 - academic.oup.com
Accurately predicting the underlying neuropathological diagnosis in patients with
behavioural variant frontotemporal dementia (bvFTD) poses a daunting challenge for …

Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia

K Rascovsky, JR Hodges, D Knopman, MF Mendez… - Brain, 2011 - academic.oup.com
Based on the recent literature and collective experience, an international consortium
developed revised guidelines for the diagnosis of behavioural variant frontotemporal …

Molecular neuropathology of frontotemporal dementia: insights into disease mechanisms from postmortem studies

IRA Mackenzie, M Neumann - Journal of neurochemistry, 2016 - Wiley Online Library
Frontotemporal dementia (FTD) is a clinical syndrome with a heterogeneous molecular
basis. The past decade has seen the discovery of several new FTD‐causing genetic …