[HTML][HTML] Perspectives on the utility of moxidectin for the control of parasitic nematodes in the face of developing anthelmintic resistance

RK Prichard, TG Geary - International Journal for Parasitology: Drugs and …, 2019 - Elsevier
Macrocyclic lactone (ML) anthelmintics are the most important class of anthelmintics
because of our high dependence on them for the control of nematode parasites and some …

Cat respiratory nematodes: Current knowledge, novel data and warranted studies on clinical features, treatment and control

S Morelli, A Diakou, M Colombo, A Di Cesare… - Pathogens, 2021 - mdpi.com
The nematodes Aelurostrongylus abstrusus, Troglostrongylus brevior and Capillaria
aerophila are the most important parasites inhabiting the airways of cats. They are receiving …

Preventive efficacy of oral moxidectin at various doses and dosage regimens against macrocyclic lactone-resistant heartworm (Dirofilaria immitis) strains in dogs

TL McTier, RH Six, A Pullins, S Chapin, K Kryda… - Parasites & vectors, 2019 - Springer
Background Moxidectin has previously shown limited efficacy (≤ 44.4%) against confirmed
macrocyclic lactone (ML)-resistant Dirofilaria immitis strains at 3 µg/kg after single and …

Dirofilarioses in cats: European guidelines from the ABCD on prevention and management

MG Pennisi, S Tasker, K Hartmann… - Journal of feline …, 2020 - journals.sagepub.com
Overview: Dirofilaria immitis and Dirofilaria repens are the most important filarial worms,
causing heartworm disease and subcutaneous dirofilariosis, respectively. D repens is …

Efficacy of semi-annual therapy of an extended-release injectable moxidectin suspension and oral doxycycline in Dirofilaria immitis naturally infected dogs

B Alberigi, JI Fernandes, JP Paiva… - Parasites & …, 2020 - Springer
Background Dirofilaria immitis is a life-threatening nematode spreading globally. Arsenical
treatment is currently recommended for removal of adult worms. However, arsenical …

Protection of dogs against canine heartworm infection 28 days after four monthly treatments with Advantage Multi® for Dogs

DD Bowman, AR Grazette, C Basel, Y Wang… - Parasites & vectors, 2016 - Springer
Background Monthly heartworm preventives are designed to protect dogs by killing
heartworms acquired the month prior to their administration, and after treatment with most …

Survey of Dirofilaria immitis antigen and antibodies to Leishmania infantum and Toxoplasma gondii in cats from Madeira Island, Portugal

M Neves, AP Lopes, C Martins, R Fino, C Paixão… - Parasites & vectors, 2020 - Springer
Abstract Background Dirofilaria immitis, Leishmania infantum and Toxoplasma gondii are
zoonotic parasites which can affect domestic cats. Considering the lack of published data …

Efficacy of imidacloprid 10%/moxidectin 1% spot-on formulation (Advocate®) in the prevention and treatment of feline aelurostrongylosis

L Heuer, G Petry, M Pollmeier, R Schaper, K Deuster… - Parasites & vectors, 2020 - Springer
Background In three randomized, controlled laboratory efficacy studies, the efficacy in the
prevention of patent infections of a topical combination of imidacloprid 10%/moxidectin …

Antifilarial chemotherapy: current options in veterinary medicine

J Ketzis, C Epe - Human and Animal Filariases: Landscape …, 2022 - Wiley Online Library
Chemotherapy options for the prevention of adult Dirofilaria immitis infections and other
filarial species in dogs and cats focus primarily on the use of macrocyclic lactones. While …

Bioanalytical method development and validation of moxidectin in plasma by LC–MS/MS: Application to in vitro metabolism

YS Chhonker, RL Sleightholm… - Biomedical …, 2019 - Wiley Online Library
Moxidectin (MOX) has recently been approved by the US Food and Drug Administration for
the treatment of river blindness in select populations. It is also being evaluated as an …