Vigorous CD8+ T cells play a crucial role in recognizing tumor cells and combating solid
tumors. How T cells efficiently recognize and target tumor antigens, and how they maintain …

Simple Summary CAR T cell therapies have been successful at treating patients with blood
cancers and are now FDA-approved therapies for various types of leukemias and …

Cancer remains a major global health challenge. Immunotherapy has revolutionized the
management of cancer, yet only a limited number of patients respond to such treatments …

Background Chimeric antigen receptor (CAR)‐T‐cell therapy has transformed cancer
treatment, leading to remarkable clinical outcomes. However, resistance continues to be a …

Introduction Adoptive immunotherapy using chimeric antigen receptor (CAR)-engineered T
cells has proven transformative in the management of B cell and plasma cel derived …

Adoptive cell therapy (ACT) can address an unmet clinical need for patients with
relapsed/refractory acute myeloid leukemia (AML), but its effect is often modest in the setting …