Mitochondrial-derived damage-associated molecular patterns amplify neuroinflammation in neurodegenerative diseases
M Lin, N Liu, Z Qin, Y Wang - Acta Pharmacologica Sinica, 2022 - nature.com
Both mitochondrial dysfunction and neuroinflammation are implicated in neurodegeneration
and neurodegenerative diseases. Accumulating evidence shows multiple links between …
and neurodegenerative diseases. Accumulating evidence shows multiple links between …
Physiological roles of hydrogen sulfide in mammalian cells, tissues, and organs
Over the last two decades, hydrogen sulfide (H2S) has emerged as an endogenous
regulator of a broad range of physiological functions. H2S belongs to the class of molecules …
regulator of a broad range of physiological functions. H2S belongs to the class of molecules …
Hydrogen sulfide is neuroprotective in Alzheimer's disease by sulfhydrating GSK3β and inhibiting Tau hyperphosphorylation
D Giovinazzo, B Bursac, JI Sbodio… - Proceedings of the …, 2021 - National Acad Sciences
Alzheimer's disease (AD), the most common cause of dementia and neurodegeneration in
the elderly, is characterized by deterioration of memory and executive and motor functions …
the elderly, is characterized by deterioration of memory and executive and motor functions …
[HTML][HTML] Hydrogen sulfide: An endogenous regulator of the immune system
N Dilek, A Papapetropoulos, T Toliver-Kinsky… - Pharmacological …, 2020 - Elsevier
Hydrogen sulfide (H 2 S) is now recognized as an endogenous signaling gasotransmitter in
mammals. It is produced by mammalian cells and tissues by various enzymes …
mammals. It is produced by mammalian cells and tissues by various enzymes …
[HTML][HTML] Polysulfide-mediated sulfhydration of SIRT1 prevents diabetic nephropathy by suppressing phosphorylation and acetylation of p65 NF-κB and STAT3
Diabetic kidney disease is known as a major cause of chronic kidney disease and end stage
renal disease. Polysulfides, a class of chemical agents with a chain of sulfur atoms, are …
renal disease. Polysulfides, a class of chemical agents with a chain of sulfur atoms, are …
Simultaneous Sensing of H2S and ATP with a Two-Photon Fluorescent Probe in Alzheimer's Disease: toward Understanding Why H2S Regulates Glutamate …
P Sun, HC Chen, S Lu, J Hai, W Guo, YH Jing… - Analytical …, 2022 - ACS Publications
Energy deprivation and reduced levels of hydrogen sulfide (H2S) in the brain is closely
associated with Alzheimer's disease (AD). However, there is currently no fluorescent probe …
associated with Alzheimer's disease (AD). However, there is currently no fluorescent probe …
Can dietary patterns prevent cognitive impairment and reduce Alzheimer's disease risk: Exploring the underlying mechanisms of effects
Alzheimer's disease (AD) is one of the fastest growing cognitive decline-related neurological
diseases. To date, effective curative strategies have remained elusive. A growing body of …
diseases. To date, effective curative strategies have remained elusive. A growing body of …
β-Hydroxybutyrate alleviates pyroptosis in MPP+/MPTP-induced Parkinson's disease models via inhibiting STAT3/NLRP3/GSDMD pathway
Z Jiang, X Yin, M Wang, Y Wang, F Li, Y Gao… - International …, 2022 - Elsevier
Background Parkinson's disease (PD) is a common neurodegenerative disease
characterized by motor symptoms and non-motor symptoms, and affects millions of people …
characterized by motor symptoms and non-motor symptoms, and affects millions of people …
Protein persulfidation: Rewiring the hydrogen sulfide signaling in cell stress response
The past few decades have witnessed significant progress in the discovery of hydrogen
sulfide (H 2 S) as a ubiquitous gaseous signaling molecule in mammalian physiology, akin …
sulfide (H 2 S) as a ubiquitous gaseous signaling molecule in mammalian physiology, akin …
[HTML][HTML] Gene regulation by antisense transcription: A focus on neurological and cancer diseases
Advances in high-throughput sequencing over the past decades have led to the
identification of thousands of non-coding RNAs (ncRNAs), which play a major role in …
identification of thousands of non-coding RNAs (ncRNAs), which play a major role in …