Recombinant Alpha, Beta, and Epsilon Toxins of Clostridium perfringens: Production Strategies and Applications as Veterinary Vaccines
MRA Ferreira, GMSG Moreira, CEP Cunha… - Toxins, 2016 - mdpi.com
Clostridium perfringens is a spore-forming, commensal, ubiquitous bacterium that is present
in the gastrointestinal tract of healthy humans and animals. This bacterium produces up to …
in the gastrointestinal tract of healthy humans and animals. This bacterium produces up to …
Vaccination against pathogenic clostridia in animals: A review
L Abdolmohammadi Khiav, A Zahmatkesh - Tropical Animal Health and …, 2021 - Springer
Clostridium is a Gram-positive, rod-shaped, anaerobic, and spore-forming bacterium, which
is found in the surrounding environments throughout the world. Clostridium species cause …
is found in the surrounding environments throughout the world. Clostridium species cause …
[HTML][HTML] Vaccination against pathogenic clostridia in animals: a review
LA Khiav, A Zahmatkesh - Tropical Animal Health and Production, 2021 - ncbi.nlm.nih.gov
Clostridium is a Gram-positive, rod-shaped, anaerobic, and spore-forming bacterium, which
is found in the surrounding environments throughout the world. Clostridium species cause …
is found in the surrounding environments throughout the world. Clostridium species cause …
Immunization of sheep with a recombinant vaccine containing immunogenic nontoxic domains of Clostridium perfringens alpha and beta toxins
RR Rodrigues, JF Motta, MRA Ferreira, CM Júnior… - Microbial …, 2023 - Elsevier
Clostridium perfringens (types A and C) can cause several diseases by secreting alpha
(CPA) and beta (CPB) exotoxins in the gastrointestinal tract. Although vaccination is the …
(CPA) and beta (CPB) exotoxins in the gastrointestinal tract. Although vaccination is the …
In silico design and in vitro analysis of a recombinant trivalent fusion protein candidate vaccine targeting virulence factor of Clostridium perfringens
Necrotic enteritis (NE) is a multifactorial disease in broiler that is caused by colonization of
Clostridium perfringens in their gastrointestinal tract. Recently several immunogenic proteins …
Clostridium perfringens in their gastrointestinal tract. Recently several immunogenic proteins …
Clostridium perfringens epsilon prototoxin mutant rpETXY30A/Y71A/H106P/Y196A as a vaccine candidate against enterotoxemia
J Du, T Wang, L Xu, C Wang, Y Liu, C Pan, X Chen… - Vaccine, 2023 - Elsevier
Epsilon toxin (ETX) is secreted by Clostridium perfringens (C. perfringens) as a relatively
inactive prototoxin (pETX), which is enzymatically activated to ETX by removing carboxy …
inactive prototoxin (pETX), which is enzymatically activated to ETX by removing carboxy …
Evaluation of the expression and immunogenicity of four versions of recombinant Clostridium perfringens beta toxin designed by bioinformatics tools
RR Rodrigues, MRA Ferreira, RA Donassolo… - Anaerobe, 2021 - Elsevier
Beta toxins (CPB) produced by Clostridium perfringens type B and C cause various
diseases in animals, and the use of toxoids is an important prophylactic measure against …
diseases in animals, and the use of toxoids is an important prophylactic measure against …
A non-toxic recombinant Clostridium septicum α toxin induces protective immunity in mice and rabbits
J Du, I Meki, Q Li, Y Liu, Z Zhu, C Pan, Y Xia, L Fu… - Toxicon, 2023 - Elsevier
Clostridium septicum alpha toxin (CSA) plays significant roles in ruminant's braxy.
Genetically engineered CSA has been shown to function as a potential vaccine candidate in …
Genetically engineered CSA has been shown to function as a potential vaccine candidate in …
A non-toxic recombinant bivalent chimeric protein rETXm3CSAm4/TMD as a potential vaccine candidate against enterotoxemia and braxy
J Du, B Liu, T Wang, Z Zhu, C Yin, Y Luo, Y Liu, X Chen - Vaccine, 2023 - Elsevier
Clostridium perfringens epsilon toxin (ETX) and Clostridium septicum alpha toxin (CSA) are
lethal and necrotizing toxins, which play key roles in enterotoxemia and braxy of ruminants …
lethal and necrotizing toxins, which play key roles in enterotoxemia and braxy of ruminants …
Clostridial binary toxins: basic understandings that include cell surface binding and an internal “Coup de Grâce”
BG Stiles - Uptake and Trafficking of Protein Toxins, 2017 - Springer
Clostridium species can make a remarkable number of different protein toxins, causing
many diverse diseases in humans and animals. The binary toxins of Clostridium botulinum …
many diverse diseases in humans and animals. The binary toxins of Clostridium botulinum …