Celiac disease (CD) is one of the most common diseases, resulting from both environmental
(gluten) and genetic factors [human leukocyte antigen (HLA) and non-HLA genes]. The …

This article examines associations between gluten, polymorphisms of the major
histocompatibility complex, and mucosal pathology representative of the spectrum of gluten …

OBJECTIVE Few studies have assessed the role of specific gastrointestinal infections in
celiac disease. We investigated whether increased frequency of rotavirus infection, a …

Amino acid sequence homology was found between viral and host encephalitogenic
protein. Immune responses were then generated in rabbits by using the viral peptide that …

Celiac disease (CD) is most probably an immunological disease, precipitated in susceptible
individuals by ingestion of wheat gliadin and related proteins from other cereals. The …

Since the discovery of HLA 60 years ago, it has contributed to the understanding of the
immune system as well as of the pathogenesis of several diseases. Aside from its essential …

Coeliac disease was described with great accuracy by Samuel Gee more than a century
ago. 1 However, the harmful effect of ingested wheat gluten was not recognised until the late …

Celiac disease (CD) is a unique autoimmune disorder in which the genetic factors
(DQ2/DQ8) and the environmental trigger (gluten) are known and necessary but not …

The human leukocyte antigen (HLA) locus is strongly associated with T cell-mediated
autoimmune disorders. HLA-DQ2. 5-mediated celiac disease (CeD) is triggered by the …

Celiac disease is a permanent intolerance to ingested gluten that results in immunologically
mediated inflammatory damage to the small-intestinal mucosa. Celiac disease is associated …