Background Radiotherapy (RT) is the chief nonsurgical method to control malignant tumors.
RT has advanced in both methodological and biological aspects over the past few decades …

The current concept in searching for new bioactive products, including mainly original active
substances with potential application in pharmacy and medicine, is based on compounds …

Due to the heterogeneity of soft tissue sarcomas (STS), the choice of the proper
perioperative treatment regimen is challenging. Neoadjuvant therapy has attracted …

Cancer is a complex multifaceted illness that affects different patients in discrete ways. For a
number of cancers the use of chemotherapy has become standard practice. Chemotherapy …

Background Radioresistance inducing by hypoxic microenvironment of hepatocellular
carcinoma is a major obstacle to clinical radiotherapy. Advanced nanomedicine provides an …

Background and Purpose: Epidemiological data suggests an excess risk of cardiovascular
disease (CVD) at low doses (0.05 and 0.1 Gy) of ionizing radiation (IR). Furthermore, the …

Radiotherapy is one of the main cancer treatments, but it may damage normal tissue and
cause various side effects. At present, radioprotective agents used in clinics have side …

Glioblastoma (GBM) is uniformly fatal with a 1-year median survival, despite best available
treatment, including radiotherapy (RT). Impacts of prior RT on tumor recurrence are poorly …

Pulmonary injury is more common in patients undergoing radiation therapy for lungs and
other thoracic malignancies. Recently with the use of most-advanced technologies powerful …

Background Nanoparticle-based therapies have emerged as a promising approach to
overcome limitations of conventional chemotherapy. Present study investigates the potential …