Biomolecules and biomarkers used in diagnosis of alcohol drinking and in monitoring therapeutic interventions

RM Nanau, MG Neuman - Biomolecules, 2015 - mdpi.com
Background: The quantitative, measurable detection of drinking is important for the
successful treatment of alcohol misuse in transplantation of patients with alcohol disorders …

Current evolutions, applications, and challenges of phosphatidylethanol analysis for clinical and forensic purposes

M Luginbühl, K Van Uytfanghe, F Stöth… - Wiley …, 2022 - Wiley Online Library
Phosphatidylethanols (PEth) are a group of abnormal phospholipids which are formed
within the human body in the presence of ethanol. As PEth accumulates in red blood cells …

Factors associated with phosphatidylethanol (PEth) sensitivity for detecting unhealthy alcohol use: An individual patient data meta‐analysis

JA Hahn, PM Murnane, E Vittinghoff… - Alcoholism: Clinical …, 2021 - Wiley Online Library
Background Objective measurement of alcohol consumption is important for clinical care
and research. Adjusting for self‐reported alcohol use, we conducted an individual …

Phosphatidylethanol compared with other blood tests as a biomarker of moderate alcohol consumption in healthy volunteers: a prospective randomized study

S Kechagias, DN Dernroth, A Blomgren… - Alcohol and …, 2015 - academic.oup.com
Aim It is generally agreed that traditional alcohol biomarkers lack in sensitivity to detect
hazardous alcohol consumption. The present study was undertaken to evaluate the ability of …

Phosphatidylethanol is Superior to Carbohydrate‐Deficient Transferrin and γ‐Glutamyltransferase as an Alcohol Marker and is a Reliable Estimate of Alcohol …

L Walther, A de Bejczy, E Löf, T Hansson… - Alcoholism: Clinical …, 2015 - Wiley Online Library
Background In clinical practice as well as research situations, it is of great importance to get
reliable information about a patient's alcohol consumption. The aim of the study was to …

Assessing phosphatidylethanol (PEth) levels reflecting different drinking habits in comparison to the alcohol use disorders identification test–C (AUDIT-C)

A Schröck, FM Wurst, N Thon, W Weinmann - Drug and Alcohol …, 2017 - Elsevier
In addition to monitoring problematic or harmful alcohol consumption, drinking experiments
indicated the potential of phosphatidylethanols (PEth) in abstinence monitoring. To date, no …

The impact of alcohol and illicit substance use on the pharmacokinetics of first-line TB drugs

M Wijk, K Gausi, S Malatesta, SE Weber… - Journal of …, 2024 - academic.oup.com
Abstract Background In South Africa, an estimated 11% of the population have high alcohol
use, a major risk factor for TB. Alcohol and other substance use are also associated with …

[HTML][HTML] Harmful alcohol use among acutely ill hospitalized medical patients in Oslo and Moscow: a cross-sectional study

S Kabashi, V Vindenes, EA Bryun, EA Koshkina… - Drug and alcohol …, 2019 - Elsevier
Background The aim was to estimate the prevalence of harmful alcohol use in relation to
socio-demographic characteristics among acutely ill medical patients, and examine …

Impact of alcohol consumption on tuberculosis treatment outcomes: a prospective longitudinal cohort study protocol

B Myers, TC Bouton, EJ Ragan, LF White… - BMC infectious …, 2018 - Springer
Background An estimated 10% of tuberculosis (TB) deaths are attributable to problematic
alcohol use globally, however the causal pathways through which problem alcohol use has …

Alcohol and mortality: combining self-reported (AUDIT-C) and biomarker detected (PEth) alcohol measures among HIV infected and uninfected

O Eyawo, KA McGinnis, AC Justice… - JAIDS Journal of …, 2018 - journals.lww.com
Background: Unhealthy alcohol use may be particularly detrimental among individuals living
with HIV and/or hepatitis C virus (HCV), and is often under-reported. Direct biomarkers of …