Biocatalysis has found numerous applications in various fields as an alternative to chemical
catalysis. The use of enzymes in organic synthesis, especially to make chiral compounds for …

The review compiles artificial cascades involving enzymes with a focus on the last 10 years.
A cascade is defined as the combination of at least two reaction steps in a single reaction …

Transaminases have attracted considerable interest in their use as biocatalysts for the
synthesis of compounds containing chiral amine units, which are widespread within the …

Despite enormous progress in protein engineering, complemented by bioprocess
engineering, the revolution awaiting the application of biocatalysis in the fine chemical …

Chiral amines are important components of 40–45% of small molecule pharmaceuticals and
many other industrially important fine chemicals and agrochemicals. Recent advances in …

Amine transaminases constitute an important class of enzymes for the synthesis of chiral
amines, which are commonly used as building blocks in pharmaceutical compounds and …

Die Biokatalyse hat in verschiedenen Einsatzgebieten Anwendung als Alternative zur
chemischen Katalyse gefunden, wobei die herausragendsten Beispiele die Herstellung …

The further implementation of new bioprocesses, using biocatalysts in various formats, for
the synthesis of chemicals is highly dependent upon effective process intensification. The …

Deracemisation via chemo-enzymatic or multi-enzymatic approaches is the optimum
substitute for kinetic resolution, which suffers from the limitation of a theoretical maximum …

Abstract α-Ketoglutarate (aKG) represents a central intermediate of cell metabolism. It is
used for medical treatments and as a chemical building block. Enzymatic cascade reactions …