Despite the continuing development of immunomodulatory agents and supportive care, the
prognosis associated with lupus nephritis (LN) has not improved substantially in the past …

Systemic lupus erythematosus (SLE) is a genetically predisposed, female-predominant
disease, characterized by multiple organ damage, that in its most severe forms can be life …

Objectives To update the EULAR recommendations for the management of systemic lupus
erythematosus (SLE) based on emerging new evidence. Methods An international Task …

Abstract Treatment-refractory lupus nephritis (LN) has a high risk of a poor outcome and is
often life-threatening. Here we report a case series of six patients (one male and five …

Over the past year, and for the first time ever, the US Food and Drug Administration
approved 2 drugs specifically for the treatment of lupus nephritis (LN). As the lupus …

Systemic lupus erythematosus (SLE) is a chronic multisystem auto-immune disease with
extremely varied clinical manifestations and a complex pathogenesis. New insights in SLE …

Systemic lupus erythematosus is a chronic autoimmune disease characterized by loss of
tolerance against nuclear and cytoplasmic self-antigens, induction of immunity and tissue …

This article is published as part of a supplement sponsored by Kidney Disease: Improving
Global Outcomes (KDIGO). The opinions or views expressed in this supplement are those of …

Nucleic acid–specific Toll-like receptors (TLRs) have been implicated in promoting disease
pathogenesis in systemic lupus erythematosus (SLE). Whether such TLRs mediate disease …

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease of unknown etiology
that primarily affects women of childbearing age. There is no disease more heterogeneous …