Novel CRISPR–Cas systems: an updated review of the current achievements, applications, and future research perspectives

S Nidhi, U Anand, P Oleksak, P Tripathi, JA Lal… - International journal of …, 2021 - mdpi.com
According to Darwin's theory, endless evolution leads to a revolution. One such example is
the Clustered Regularly Interspaced Palindromic Repeats (CRISPR)–Cas system, an …

Application of different types of CRISPR/Cas-based systems in bacteria

Z Liu, H Dong, Y Cui, L Cong, D Zhang - Microbial cell factories, 2020 - Springer
As important genome editing tools, CRISPR/Cas systems, especially those based on type II
Cas9 and type V Cas12a, are widely used in genetic and metabolic engineering of bacteria …

In vitro prototyping and rapid optimization of biosynthetic enzymes for cell design

AS Karim, QM Dudley, A Juminaga, Y Yuan… - Nature Chemical …, 2020 - nature.com
The design and optimization of biosynthetic pathways for industrially relevant, non-model
organisms is challenging due to transformation idiosyncrasies, reduced numbers of …

Syngas fermentation process development for production of biofuels and chemicals: A review

X Sun, HK Atiyeh, RL Huhnke, RS Tanner - Bioresource Technology …, 2019 - Elsevier
Syngas is produced by thermochemical conversion, eg, pyrolysis and gasification, of
biomass, animal waste, coal, municipal solid waste and other carbonaceous materials, or …

Stepping on the gas to a circular economy: accelerating development of carbon-negative chemical production from gas fermentation

N Fackler, BD Heijstra, BJ Rasor… - Annual review of …, 2021 - annualreviews.org
Owing to rising levels of greenhouse gases in our atmosphere and oceans, climate change
poses significant environmental, economic, and social challenges globally. Technologies …

Advances in industrial biotechnology using CRISPR-Cas systems

PD Donohoue, R Barrangou, AP May - Trends in biotechnology, 2018 - cell.com
The term 'clustered regularly interspaced short palindromic repeats'(CRISPR) has recently
become synonymous with the genome-editing revolution. The RNA-guided endonuclease …

Pollution to products: recycling of 'above ground'carbon by gas fermentation

M Köpke, SD Simpson - Current Opinion in Biotechnology, 2020 - Elsevier
Climate crisis and rapid population growth are posing some of the most urgent challenges to
mankind and have intensified the need for the deployment of carbon recycling and carbon …

Advances in systems metabolic engineering of autotrophic carbon oxide-fixing biocatalysts towards a circular economy

M Pavan, K Reinmets, S Garg, AP Mueller… - Metabolic …, 2022 - Elsevier
High levels of anthropogenic CO 2 emissions are driving the warming of global climate. If
this pattern of increasing emissions does not change, it will cause further climate change …

Bacterial anaerobic synthesis gas (syngas) and CO2+ H2 fermentation

FR Bengelsdorf, MH Beck, C Erz, S Hoffmeister… - Advances in applied …, 2018 - Elsevier
Anaerobic bacterial gas fermentation gains broad interest in various scientific, social, and
industrial fields. This microbial process is carried out by a specific group of bacterial strains …

Applications of CRISPR/Cas system to bacterial metabolic engineering

S Cho, J Shin, BK Cho - International journal of molecular sciences, 2018 - mdpi.com
The clustered regularly interspaced short palindromic repeats/CRISPR-associated
(CRISPR/Cas) adaptive immune system has been extensively used for gene editing …