Focused ultrasound (FUS) is a disruptive medical technology, and its implementation in the
clinic represents the culmination of decades of research. Lying at the convergence of …

Background There is an emerging need for noninvasive neuromodulation techniques to
improve patient outcomes while minimizing adverse events and morbidity. Low-intensity …

Focused ultrasound (FUS) in the presence of microbubbles can transiently open the blood-
brain barrier (BBB) to increase therapeutic agent penetration at the targeted brain site to …

Background The subthalamic nucleus is the preferred neurosurgical target for deep-brain
stimulation to treat cardinal motor features of Parkinson's disease. Focused ultrasound is an …

Brain tumors are particularly challenging malignancies, due to their location in a structurally
and functionally distinct part of the human body–the central nervous system (CNS). The CNS …

OBJECTIVE Thalamotomy of the ventral intermediate nucleus (VIM) is effective in alleviating
medication-resistant tremor in patients with essential tremor (ET) and Parkinson's disease …

Since Lynn and colleagues first described the use of focused ultrasound (FUS) waves for
intracranial ablation in 1942, many strides have been made toward the treatment of several …

OBJECTIVE Glioblastoma (GBM) remains fatal due to the blood-brain barrier (BBB), which
interferes with the delivery of chemotherapeutic agents. The purpose of this study was to …

Background Following the emergence of magnetic resonance‐guided focused ultrasound
as a promising tool for movement disorder surgery, thalamotomy for essential tremor using …

OBJECTIVE The authors report their experience in treating patients suffering from
medication-resistant essential tremor (ET) with MR-guided focused ultrasound (MRgFUS) …