The animal model deals with the species other than the human, as it can imitate the disease
progression, its' diagnosis as well as a treatment similar to human. Discovery of a drug …

Intervertebral disc (IVD) degeneration (IDD) is a pathological process that commonly occurs
throughout the human life span and is a major cause of lower back pain. Better elucidation …

Low back pain is a highly prevalent, chronic, and costly medical condition predominantly
triggered by intervertebral disc degeneration (IDD). IDD is often caused by structural and …

Purpose Low back pain (LBP), a widely prevalent and costly disease around the world, is
mainly caused by intervertebral disc (IVD) degeneration (IDD). Although numerous factors …

Intervertebral disc degeneration (IDD) is the leading cause of low back pain (LBP) and
disability in the elderly, imposing significant public health and economic burden worldwide …

Low back pain is a major public health concern experienced by 80% of the world's
population during their lifetime, which is closely associated with intervertebral disc (IVD) …

Preclinical studies involving large animal models aim to recapitulate the clinical situation as
much as possible and bridge the gap from benchtop to bedside. To date, studies …

Intervertebral disc degeneration is a cascade of cellular, structural, and biomechanical
changes that is strongly implicated as a cause of low-back pain. Current treatment strategies …

Intervertebral disc degeneration (IVDD), a widely recognized cause of lower back pain, is
the leading cause of disability worldwide. A myriad of preclinical in vivo animal models of …

Intervertebral disc degeneration (IVDD) is a general disorder that results in low back pain
and disability among many affected individuals. However, the current treatments for IVDD …