Interest in the biology of the intervertebral disc has grown significantly over the past 2
decades, driven mainly by studies aimed at developing biological therapies for repairing …

Background Low back pain and sciatica caused by intervertebral disc (IVD) disease are
associated with inflammatory responses. The cytokine interleukin 17 (IL-17) is elevated in …

The mechanical behaviour and cellular metabolism of intervertebral discs (IVDs) and
articular cartilage are strongly influenced by their proteoglycan content and associated …

Chronic back and neck pain is a prevalent disability, often caused by degeneration of the
intervertebral disc. Because current treatments for this condition are less than satisfactory, a …

Low back pain (LBP) is a common worldwide disease that causes an enormous social
economic burden. Intervertebral disc degeneration (IDD) is considered as a major cause of …

Inflammation plays an important role in the pathogenesis of intervertebral disc (IVD)
degeneration. The proinflammatory cytokine tumor necrosis factor alpha (TNF‐α) has shown …

The nucleus pulposus (NP) of intervertebral discs experiences dynamic changes in tissue
osmolarity because of diurnal loading of the spine. TonEBP/NFAT5 is a transcription factor …

Notochordal cells (NCs) reside in the core of the healthy disc and produce soluble factors
that can stimulate nucleus pulposus cells (NPCs). These NC-derived factors may be applied …

Background: Neuropathic pain is one of the common complications after spinal cord injury
(SCI), affecting individuals' quality of life. The molecular mechanism for neuropathic pain …

miR-206 对腰椎间盘突出症大鼠髓核炎症,镇痛及自噬相关蛋白的作用机制 Page 1 1712|中国
组织工程研究|第28卷|第11期|2024年4月 中国组织工程研究 Chinese Journal of Tissue …