We review here the recently emerging relationship between epithelial-mesenchymal
transition (EMT) and breast cancer stem cells (BCSC), and provide analyses of published …

Inherited neuropathies are caused by dominant or recessive mutations in genes that are
expressed by neurons and/or Schwann cells. In demyelinating neuropathies, the deleterious …

Abstract Naturally occurring CD25+ CD4+ regulatory T cells (Tregs) actively engage in the
maintenance of immunologic self-tolerance and immunoregulation. They specifically …

Tight junctions form selective barriers that regulate paracellular transport across epithelia. A
large family of tetraspanning cell-cell adhesion proteins called claudins create the barrier …

An intrachromosomal duplication containing the PMP22 gene is associated with the human
hereditary peripheral neuropathy Charcot-Marie-Tooth disease type 1A, and PMP22 …

Nephrotic syndrome (NS) is a genetically heterogeneous group of diseases that are divided
into steroid-sensitive NS (SSNS) and steroid-resistant NS (SRNS). SRNS inevitably leads to …

The binding of extracellular ATP to the P2X 7 receptor opens an integral cation-permeable
channel; it also leads to membrane blebbing and, in certain immune cells, interleukin-1β …

The presence of common genomic deletions in the 19q13 chromosomal region in
neuroblastomas and gliomas strongly suggests the presence of a putative tumor suppressor …

The epithelial membrane protein genes 1, 2, and 3 (EMP1, EMP2, and EMP3) belong to the
peripheral myelin protein 22-kDa (PMP22) gene family, which consists of at least seven …

Hereditary neuropathy with liability to pressure palsy (HNPP) is associated with a
heterozygous 1.5 megabase deletion on chromosome 17 that includes the peripheral myelin …