Co-encapsulation of tamoxifen and quercetin in polymeric nanoparticles: implications on oral bioavailability, antitumor efficacy, and drug-induced toxicity

AK Jain, K Thanki, S Jain - Molecular pharmaceutics, 2013 - ACS Publications
The present investigation reports the preparation, optimization, and characterization of orally
administrable PLGA-NPs co-encapsulated with tamoxifen (Tmx) and quercetin (QT). The …

The effect of the oral administration of polymeric nanoparticles on the efficacy and toxicity of tamoxifen

AK Jain, NK Swarnakar, C Godugu, RP Singh, S Jain - Biomaterials, 2011 - Elsevier
The present investigation reports on the conditions for preparation of tamoxifen loaded
PLGA nanoparticles (Tmx-NPs) for oral administration. Tmx-NPs with> 85% entrapment …

Substituent effects on the self-assembly/coassembly and hydrogelation of phenylalanine derivatives

W Liyanage, BL Nilsson - Langmuir, 2016 - ACS Publications
Supramolecular hydrogels derived from the self-assembly of organic molecules have been
exploited for applications ranging from drug delivery to tissue engineering. The relationship …

Encapsulated energy-transfer cassettes with extremely well resolved fluorescent outputs

Y Ueno, J Jose, A Loudet, C Pérez-Bolívar… - Journal of the …, 2011 - ACS Publications
This paper concerns the development of water-compatible fluorescent imaging probes with
tunable photonic properties that can be excited at a single wavelength. Bichromophoric …

Thymoquinone loaded mesoporous silica nanoparticles retard cell invasion and enhance in vitro cytotoxicity due to ROS mediated apoptosis in HeLa and MCF-7 cell …

S Goel, P Mishra - Materials Science and Engineering: C, 2019 - Elsevier
Thymoquinone (TQ) loaded monodispersed mesoporous silica nanoparticles (TQ-MSNPs)
with size of 188±3 nm were prepared and characterized using DLS, TEM and FTIR. These …

Pleomorphism in Biological Units of Life: Morphological Heterogeneity in Cells Does Not Translate Uniformly to Subcellular Components

P Singh, A Mittal - ACS omega, 2024 - ACS Publications
The interplay of the three-dimensional (3D) distribution of various subcellular components
and their interactions are expected to control overall cellular morphology in biology. In this …

Amyloid‐Inspired Optical Waveguides from Multicomponent Crystalline Microtubes

W Liyanage, NMB Cogan, BL Nilsson - ChemNanoMat, 2016 - Wiley Online Library
Crystalline microtubes formed by a spontaneous transition from self‐assembled hydrogel
fibrils of Fmoc‐4‐NO2‐Phe act as optical waveguides when coassembled with amyloid …

Permeation Behaviour of Lysozyme-Loaded Poly (Lactic-co-Glycolic Acid) Nanoparticles Through Porcine Oesophageal Mucosa and Its Microscopic Study

R Shankarayan, P Mishra - Journal of Nanopharmaceutics and …, 2016 - ingentaconnect.com
Pharmaceutical proteins and peptides remain poorly bioavailable when administered orally
due to their low mucosal permeability and lack of stability in the gastrointestinal …