The cushioning function of large arteries encompasses distension during systole and recoil
during diastole which transforms pulsatile flow into a steady flow in the microcirculation …

Prevention of cardiovascular disease (CVD) remains one of the largest public health
challenges of our time. Identifying individuals at increased cardiovascular risk at an …

Propagation of the pressure wave along the arterial tree (pulse wave velocity [PWV]) is
related to the intrinsic elasticity of the arterial wall. PWV is increased in stiffer arteries and …

Background: Although a high intake of some flavonoid subclasses may reduce
cardiovascular disease mortality, data regarding the in vivo mechanisms of action are …

Vascular disease is still the leading cause of morbidity and mortality in the Western world,
and the primary cause of myocardial infarction, stroke, and ischemia. The biology of vascular …

Previous human studies have shown that large-artery stiffness contributes to an age-related
decrease in cardiovagal baroreflex sensitivity. Whether this is also true with sympathetic …

Rationale: One measure of protein glycosylation (GlycA) has been reported to predict higher
cardiovascular risk by reflecting inflammatory pathways. Objective: The main objective of this …

Epidemiological studies have shown an association between bone loss/osteoporosis and
vascular calcification (VC). Recent studies have implicated the Wnt signalling pathway in the …

In men and women, there is a significant association between the risk of cardiovascular
event (myocardial infarction, stroke) and risk of major fragility fracture (hip, vertebra) …

Cardiovascular disease is the leading cause of death among patients with chronic kidney
disease (CKD). Vascular calcification (VC) is one of the independent risk factors associated …