Cell polarization is crucial for the development of multicellular organisms, and aberrant cell
polarization contributes to various diseases, including cancer. How cell polarity is …

As part of the blood-brain-barrier, astrocytes are ideally positioned between cerebral
vasculature and neuronal synapses to mediate nutrient uptake from the systemic circulation …

Manganese (Mn) is an essential trace nutrient that is potentially toxic at high levels of
exposure. As a constituent of numerous enzymes and a cofactor, manganese plays an …

Background The monocarboxylate transporter 8 (MCT8) plays a vital role in maintaining
brain thyroid hormone homeostasis. This transmembrane transporter is expressed at the …

Thyroid hormones are crucial during development and in the adult brain. Of interest,
fluctuations in the levels of thyroid hormones at various times during development and …

Until recently, the neuroscience community held the belief that glial cells such as astrocytes
and oligodendrocytes functioned solely as “support” cells of the brain. In this role, glial cells …

Corticosteroids (CS) act synergistically with thyroid hormone (TH) to accelerate amphibian
metamorphosis. Earlier studies showed that CS increase nuclear 3, 5, 3′-triiodothyronine …

Maternal hypothyroxinemia can induce neurodevelopmental impairments in the developing
fetus. We here review recent studies on the epidemiology and molecular mechanisms …

Thyroid hormone (T3) regulates the growth and differentiation of rat cerebellar astrocytes.
Previously, we have demonstrated that these effects are due, at least in part, to the …

In older men there is a multiple hormonal dysregulation with a relative prevalence of
catabolic hormones such as thyroid hormones and cortisol and a decline in anabolic …