[HTML][HTML] Isolation and characterization of urinary extracellular vesicles: implications for biomarker discovery

ML Merchant, IM Rood, JKJ Deegens… - Nature Reviews …, 2017 - nature.com
Urine is a valuable diagnostic medium and, with the discovery of urinary extracellular
vesicles, is viewed as a dynamic bioactive fluid. Extracellular vesicles are lipid-enclosed …

Understanding the extracellular vesicle surface for clinical molecular biology

S Hallal, Á Tűzesi, GE Grau… - Journal of …, 2022 - Wiley Online Library
Extracellular vesicles (EVs) are lipid‐membrane enclosed nanoparticles that play significant
roles in health and disease. EVs are abundant in body fluids and carry an array of molecules …

Urinary extracellular vesicles: A position paper by the Urine Task Force of the International Society for Extracellular Vesicles

U Erdbrügger, CJ Blijdorp, IV Bijnsdorp… - Journal of …, 2021 - Wiley Online Library
Urine is commonly used for clinical diagnosis and biomedical research. The discovery of
extracellular vesicles (EV) in urine opened a new fast‐growing scientific field. In the last …

[HTML][HTML] Identification of distinct nanoparticles and subsets of extracellular vesicles by asymmetric flow field-flow fractionation

H Zhang, D Freitas, HS Kim, K Fabijanic, Z Li… - Nature cell …, 2018 - nature.com
The heterogeneity of exosomal populations has hindered our understanding of their
biogenesis, molecular composition, biodistribution and functions. By employing asymmetric …

Protein glycosylation and tumor microenvironment alterations driving cancer hallmarks

A Peixoto, M Relvas-Santos, R Azevedo… - Frontiers in …, 2019 - frontiersin.org
Decades of research have disclosed a plethora of alterations in protein glycosylation that
decisively impact in all stages of disease and ultimately contribute to more aggressive cell …

Phosphoproteins in extracellular vesicles as candidate markers for breast cancer

IH Chen, L Xue, CC Hsu, JSP Paez… - Proceedings of the …, 2017 - National Acad Sciences
The state of protein phosphorylation can be a key determinant of cellular physiology such as
early-stage cancer, but the development of phosphoproteins in biofluids for disease …

Extracellular vesicles and their emerging roles as cellular messengers in endocrinology: an endocrine society scientific statement

C Salomon, S Das, U Erdbrügger, R Kalluri… - Endocrine …, 2022 - academic.oup.com
During the last decade, there has been great interest in elucidating the biological role of
extracellular vesicles (EVs), particularly, their hormone-like role in cell-to-cell …

Glycosylation of extracellular vesicles: current knowledge, tools and clinical perspectives

C Williams, F Royo, O Aizpurua-Olaizola… - Journal of …, 2018 - Taylor & Francis
It is now acknowledged that extracellular vesicles (EVs) are important effectors in a vast
number of biological processes through intercellular transfer of biomolecules. Increasing …

[HTML][HTML] Metabolomic profiling of extracellular vesicles and alternative normalization methods reveal enriched metabolites and strategies to study prostate cancer …

M Puhka, M Takatalo, ME Nordberg, S Valkonen… - Theranostics, 2017 - ncbi.nlm.nih.gov
Body fluids are a rich source of extracellular vesicles (EVs), which carry cargo derived from
the secreting cells. So far, biomarkers for pathological conditions have been mainly …

Mitochondrial protein enriched extracellular vesicles discovered in human melanoma tissues can be detected in patient plasma

SC Jang, R Crescitelli, A Cvjetkovic… - Journal of …, 2019 - Taylor & Francis
Extracellular vesicles (EVs), including exosomes and microvesicles, are secreted from all
cells, and convey messages between cells in health and disease. However, the diversity of …