Individuals with Down syndrome (DS) have high levels of oxidative stress throughout the
lifespan. Mouse models of DS share some structural and functional abnormalities that …

Different metabolic profiles as well as comorbidities are common in people with Down
Syndrome (DS). Therefore it is relevant to know whether micronutrient levels in people with …

There is currently no effective pharmacological therapy to improve the cognitive dysfunction
of individuals with Down syndrome (DS). Due to the overexpression of several chromosome …

Much attention has been devoted to neurodegenerative diseases involving redox
processes. This review comprises an update involving redox processes reported in the …

Aims The aim of this study was to evaluate the antioxidant status and oxidative stress
biomarkers in the blood of children and teenagers with Down syndrome. Main methods The …

This work investigates the role of metabolite levels in the intellectual impairment of subjects
with Down syndrome (DS). Homocysteine, folate, vitamin B12, uric acid (UA), creatinine …

We previously demonstrated that systemic oxidative stress is present in Down syndrome
(DS) patients. In the present study we investigated the antioxidant status in the peripheral …

Urinary biomarkers of oxidative stress have been little studied in adults with Down syndrome
(DS), usually no more than two biomarkers have been measured in the population studied …

Homocysteine is an independent risk factor for various cardiovascular diseases. There are
two ways to remove homocysteine from embryonic cardiac cells: remethylation to form …

Introduction A controlled intervention trial was conducted to assess the impact of spinach
consumption on DNA stability in lymphocytes and on health-related biochemical …