Long COVID science, research and policy

Z Al-Aly, H Davis, L McCorkell, L Soares… - Nature medicine, 2024 - nature.com
Long COVID represents the constellation of post-acute and long-term health effects caused
by SARS-CoV-2 infection; it is a complex, multisystem disorder that can affect nearly every …

[HTML][HTML] Mechanisms of long COVID and the path toward therapeutics

MJ Peluso, SG Deeks - Cell, 2024 - cell.com
Long COVID, a type of post-acute sequelae of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2)(PASC) defined by medically unexplained symptoms following …

Large-scale phenotyping of patients with long COVID post-hospitalization reveals mechanistic subtypes of disease

F Liew, C Efstathiou, S Fontanella, M Richardson… - Nature …, 2024 - nature.com
One in ten severe acute respiratory syndrome coronavirus 2 infections result in prolonged
symptoms termed long coronavirus disease (COVID), yet disease phenotypes and …

Long COVID-19 pathophysiology: what do we know so far?

NR Tziolos, P Ioannou, S Baliou, DP Kofteridis - Microorganisms, 2023 - mdpi.com
Long COVID-19 is a recognized entity that affects millions of people worldwide. Its broad
clinical symptoms include thrombotic events, brain fog, myocarditis, shortness of breath …

Genetic risk factors for severe and fatigue dominant long COVID and commonalities with ME/CFS identified by combinatorial analysis

K Taylor, M Pearson, S Das, J Sardell… - Journal of Translational …, 2023 - Springer
Background Long COVID is a debilitating chronic condition that has affected over 100
million people globally. It is characterized by a diverse array of symptoms, including fatigue …

Long COVID in pediatrics—epidemiology, diagnosis, and management

N Toepfner, F Brinkmann, S Augustin… - European Journal of …, 2024 - Springer
This review summarizes current knowledge on post-acute sequelae of COVID-19 (PASC)
and post-COVID-19 condition (PCC) in children and adolescents. A literature review was …

Long COVID: molecular mechanisms and detection techniques

A Constantinescu-Bercu, A Lobiuc… - International Journal of …, 2023 - mdpi.com
Long COVID, also known as post-acute sequelae of SARS-CoV-2 infection (PASC), has
emerged as a significant health concern following the COVID-19 pandemic. Molecular …

Susceptibility of SARS-CoV2 infection in children

N Cotugno, D Amodio, D Buonsenso… - European journal of …, 2023 - Springer
Coronavirus disease 2019 in children presents with distinct phenotype in comparison to
adults. Overall, the pediatric infection with a generally milder clinical course of the acute …

The Silent Syndrome of Long COVID and Gaps in Scientific Knowledge: A Narrative Review

R da Silva, ACR Vallinoto, EJM Dos Santos - Viruses, 2024 - pmc.ncbi.nlm.nih.gov
COVID-19 is still a major public health concern, mainly due to the persistence of symptoms
or the appearance of new symptoms. To date, more than 200 symptoms of long COVID (LC) …

The impact of COVID-19 on pulmonary, neurological, and cardiac outcomes: evidence from a Mendelian randomization study

PU Shenoy, H Udupa, J Ks, S Babu, NK… - Frontiers in Public …, 2023 - frontiersin.org
Background Long COVID is a clinical entity characterized by persistent health problems or
development of new diseases, without an alternative diagnosis, following SARS-CoV-2 …