Respiratory delivery of passive immunotherapies for SARS-CoV-2 prophylaxis and therapy

D Focosi, F Maggi - Human Vaccines & Immunotherapeutics, 2023 - Taylor & Francis
Convalescent plasma has been extensively tested during the COVID-19 pandemic as a
transfusion product. Similarly, monoclonal antibodies have been largely administered either …

Polyclonal anti-whole cell IgY passive immunotherapy shields against P. aeruginosa-induced acute pneumonia and burn wound infections in murine models

TS Ahmadi, B Behrouz, SL Mousavi Gargari - Scientific Reports, 2024 - nature.com
Pseudomonas aeruginosa (PA) is a multidrug-resistant (MDR) opportunistic pathogen
causing severe hospital-, and community-acquired infections worldwide. Thus, the …

Egg-derived anti-SARS-CoV-2 immunoglobulin Y (IgY) with broad variant activity as intranasal prophylaxis against COVID-19

LR Frumkin, M Lucas, CL Scribner… - Frontiers in …, 2022 - frontiersin.org
COVID-19 emergency use authorizations and approvals for vaccines were achieved in
record time. However, there remains a need to develop additional safe, effective, easy-to …

[HTML][HTML] Passive immunization of mice with IgY anti-H5N1 protects against experimental influenza virus infection and allows development of protective immunity

M Eriksson, S Nylén, KO Grönvik - Vaccine, 2024 - Elsevier
Influenza virus contributes substantially to the global human and animal disease burden. To
protect individuals against disease, strategies are needed to minimize the time an individual …

Antiviral immunoglobulins of chicken egg yolk for potential prevention of SARS-CoV-2 infection

E Ravlo, L Evensen, G Sanson, S Hildonen, A Ianevski… - Viruses, 2022 - mdpi.com
Background: Some viruses cause outbreaks, which require immediate attention.
Neutralizing antibodies could be developed for viral outbreak management. However, the …

Peruvian contributions to scientific publications on experimental research against COVID-19: a systematic review

K Coronel-Monje, MA Candia-Puma… - …, 2023 - f1000research.com
Background One of the countries most adversely affected by the COVID-19 outbreak was
Peru. Worldwide scientific knowledge creation has significantly grown because of this …

[HTML][HTML] HR121 targeting HR2 domain in S2 subunit of spike protein can serve as a broad-spectrum SARS-CoV-2 inhibitor via intranasal administration

Y Lu, F Shen, WQ He, AQ Li, MH Li, XL Feng… - … Pharmaceutica Sinica B, 2023 - Elsevier
The continuously emerging SARS-CoV-2 variants pose a great challenge to the efficacy of
current drugs, this necessitates the development of broad-spectrum antiviral drugs. In the …

Development of polyclonal chicken egg yolk immunoglobulin Y (IgY) antibodies targeting SARS-CoV-2 multi-epitope antigen

A Fibriani, K Naisanu, N Yamahoki… - Journal of Virological …, 2025 - Elsevier
Severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) is the primary cause of the
Coronavirus disease 2019 (COVID-19) pandemic, which affects millions of people …

Opinion: The use of chicken IgY in the control of pandemics

MG Wallach - Frontiers in Immunology, 2022 - frontiersin.org
Discussion Over the course of human evolution, we have faced major pandemics caused by
both viral and bacterial pathogens. The Spanish flu of 1917 was the most devastating and …

[HTML][HTML] COVID-19 prophylaxis with immunoglobulin Y (IgY) for the world population: The critical role that governments and non-governmental organizations can play

LR Frumkin, M Lucas, M Wallach… - Journal of Global …, 2022 - ncbi.nlm.nih.gov
CONCLUSION The global death toll from COVID-19 is now over six million, with estimates of
excess deaths associated with COVID-19 at least double that figure during 2020 and 2021 …