The role of neutrophils in hypertension
It is well accepted that the immune system and some cells from adaptive and innate
immunity are necessary for the initiation/perpetuation of arterial hypertension (AH) …
immunity are necessary for the initiation/perpetuation of arterial hypertension (AH) …
Molecular biochemical aspects of salt (sodium chloride) in inflammation and immune response with reference to hypertension and type 2 diabetes mellitus
UN Das - Lipids in Health and Disease, 2021 - Springer
Obesity, insulin resistance, type 2 diabetes mellitus (T2DM) and hypertension (HTN) are
common that are associated with low-grade systemic inflammation. Diet, genetic factors …
common that are associated with low-grade systemic inflammation. Diet, genetic factors …
Diosmetin ameliorates vascular dysfunction and remodeling by modulation of Nrf2/HO-1 and p-JNK/p-NF-κB expression in hypertensive rats
S Meephat, P Prasatthong, P Potue, S Bunbupha… - Antioxidants, 2021 - mdpi.com
Diosmetin is a citrus flavonoid that has antioxidant and anti-inflammatory effects. This study
examined the effect of diosmetin on blood pressure and vascular alterations and its …
examined the effect of diosmetin on blood pressure and vascular alterations and its …
[HTML][HTML] Irisin attenuates vascular remodeling in hypertensive mice induced by Ang II by suppressing Ca2+-dependent endoplasmic reticulum stress in VSMCs
R Li, C Zhuo, X Yan, H Li, L Lin, L Li… - … Journal of Biological …, 2024 - ncbi.nlm.nih.gov
Vascular remodeling plays a vital role in hypertensive diseases and is an important target for
hypertension treatment. Irisin, a newly discovered myokine and adipokine, has been found …
hypertension treatment. Irisin, a newly discovered myokine and adipokine, has been found …
Caffeic acid modulates activation of neutrophils and attenuates sepsis-induced organ injury by inhibiting 5-LOX/LTB4 pathway
C Yu, Y Wang, S Ren, Z Liu, C Zhu, Q Liu, H Li… - International …, 2023 - Elsevier
Background Sepsis is a critical systemic inflammatory syndrome which usually leads to
multiple organ dysfunction. Caffeic acid (CA), a phenolic compound derived from various …
multiple organ dysfunction. Caffeic acid (CA), a phenolic compound derived from various …
Co-administration of metformin and/or glibenclamide with losartan reverse NG-nitro-l-arginine-methyl ester-streptozotocin-induced hypertensive diabetes and …
Over the years, there have been opinions on whether to reduced blood pressure (BP) to a
different levels in patients with diabetes mellitus. Hence, this study investigated the efficacy …
different levels in patients with diabetes mellitus. Hence, this study investigated the efficacy …
Hypertensive Rats Treated Chronically With Nω-Nitro-L-Arginine Methyl Ester (L-NAME) Induced Disorder of Hepatic Fatty Acid Metabolism and Intestinal …
B Li, X He, SS Lei, FC Zhou, NY Zhang… - Frontiers in …, 2020 - frontiersin.org
Nω-nitro-L-arginine methyl ester (L-NAME), an inhibitor of nitric oxide (NO) biosynthesis,
results in hypertension and liver injury. This study aimed at investigating the changes of liver …
results in hypertension and liver injury. This study aimed at investigating the changes of liver …
[HTML][HTML] Co-exposure to particulate matter and humidity increases blood pressure in hypertensive mice via the TRPV4-cPLA2-COX2 pathway
M Guo, B Li, Q Peng, R Yao, Y Wu, P Ma, C Du… - Ecotoxicology and …, 2023 - Elsevier
Epidemiological studies have demonstrated that particulate matter (PM) can induce or
exacerbate hypertension. High relative humidity has been associated with elevated blood …
exacerbate hypertension. High relative humidity has been associated with elevated blood …
Evaluation of Potential Herb-Drug Interactions Between Shengmai Injection and Losartan Potassium in Rat and In Vitro
Z Niu, T Qiang, W Lin, Y Li, K Wang, D Wang… - Frontiers in …, 2022 - frontiersin.org
Aim: The present study aimed to explore the potential herb-drug interactions (HDI) between
Shengmai injection (SMI) and losartan potassium (LOS) based on the expression profiles of …
Shengmai injection (SMI) and losartan potassium (LOS) based on the expression profiles of …
Thrombin inhibition prevents endothelial dysfunction and reverses 20-HETE overproduction without affecting blood pressure in angiotensin II-induced hypertension in …
A Kij, A Bar, K Przyborowski, B Proniewski… - International Journal of …, 2021 - mdpi.com
Angiotensin II (Ang II) induces hypertension and endothelial dysfunction, but the
involvement of thrombin in these responses is not clear. Here, we assessed the effects of the …
involvement of thrombin in these responses is not clear. Here, we assessed the effects of the …