CrRLK1L receptor-like kinases: not just another brick in the wall

H Lindner, LM Müller, A Boisson-Dernier… - Current opinion in plant …, 2012 - Elsevier
In plants, receptor-like kinases regulate many processes during reproductive and vegetative
development. The Arabidopsis subfamily of Catharanthus roseus RLK1-like kinases …

The molecular basis of gamete recognition in mice and humans

MA Avella, B Xiong, J Dean - Molecular human reproduction, 2013 - academic.oup.com
Successful fertilization heralds the onset of development and requires both gamete
recognition and a definitive block to polyspermy. Sperm initially bind and penetrate the …

A recurrent missense mutation in ZP3 causes empty follicle syndrome and female infertility

T Chen, Y Bian, X Liu, S Zhao, K Wu, L Yan, M Li… - The American Journal of …, 2017 - cell.com
Empty follicle syndrome (EFS) is defined as the failure to aspirate oocytes from mature
ovarian follicles during in vitro fertilization. Except for some cases caused by …

Zona pellucida genes and proteins: essential players in mammalian oogenesis and fertility

PM Wassarman, ES Litscher - Genes, 2021 - mdpi.com
All mammalian oocytes and eggs are surrounded by a relatively thick extracellular matrix
(ECM), the zona pellucida (ZP), that plays vital roles during oogenesis, fertilization, and …

Mutant ZP1 in familial infertility

HL Huang, C Lv, YC Zhao, W Li, XM He… - … England Journal of …, 2014 - Mass Medical Soc
The human zona pellucida is composed of four glycoproteins (ZP1, ZP2, ZP3, and ZP4) and
has an important role in reproduction. Here we describe a form of infertility with an …

Mammalian zona pellucida glycoproteins: structure and function during fertilization

SK Gupta, B Bhandari, A Shrestha, BK Biswal… - Cell and tissue …, 2012 - Springer
Zona pellucida (ZP) is a glycoproteinaceous translucent matrix that surrounds the
mammalian oocyte and plays a critical role in the accomplishment of fertilization. In humans …

Zinc sparks induce physiochemical changes in the egg zona pellucida that prevent polyspermy

EL Que, FE Duncan, AR Bayer, SJ Philips… - Integrative …, 2017 - academic.oup.com
During fertilization or chemically-induced egg activation, the mouse egg releases billions of
zinc atoms in brief bursts known as 'zinc sparks.'The zona pellucida (ZP), a glycoprotein …

Mammalian egg coat modifications and the block to polyspermy

E Fahrenkamp, B Algarra… - Molecular Reproduction …, 2020 - Wiley Online Library
Fertilization by more than one sperm causes polyploidy, a condition that is generally lethal to
the embryo in the majority of animal species. To prevent this occurrence, eggs have …

New insights into the mammalian egg zona pellucida

C Moros-Nicolás, P Chevret… - International Journal of …, 2021 - mdpi.com
Mammalian oocytes are surrounded by an extracellular coat called the zona pellucida (ZP),
which, from an evolutionary point of view, is the most ancient of the coats that envelope …

The molecular mechanisms mediating mammalian fertilization

HH Bhakta, FH Refai, MA Avella - Development, 2019 - journals.biologists.com
Fertilization is a key biological process in which the egg and sperm must recognize one
another and fuse to form a zygote. Although the process is a continuum, mammalian …