[HTML][HTML] Normal and glaucomatous outflow regulation
Glaucoma remains only partially understood, particularly at the level of intraocular pressure
(IOP) regulation. Trabecular meshwork (TM) and Schlemm's canal inner wall endothelium …
(IOP) regulation. Trabecular meshwork (TM) and Schlemm's canal inner wall endothelium …
In vivo measurement of trabecular meshwork stiffness in a corticosteroid-induced ocular hypertensive mouse model
Ocular corticosteroids are commonly used clinically. Unfortunately, their administration
frequently leads to ocular hypertension, ie, elevated intraocular pressure (IOP), which, in …
frequently leads to ocular hypertension, ie, elevated intraocular pressure (IOP), which, in …
Viscoelastic biomechanical properties of the conventional aqueous outflow pathway tissues in healthy and glaucoma human eyes
Background: Although the tissues comprising the ocular conventional outflow pathway have
shown strong viscoelastic mechanical response to aqueous humor pressure dynamics, the …
shown strong viscoelastic mechanical response to aqueous humor pressure dynamics, the …
Developing an experimental-computational workflow to study the biomechanics of the human conventional aqueous outflow pathway
The aqueous humor actively interacts with the trabecular meshwork (TM), juxtacanalicular
tissue (JCT), and Schlemm's canal (SC) through a dynamic fluid-structure interaction (FSI) …
tissue (JCT), and Schlemm's canal (SC) through a dynamic fluid-structure interaction (FSI) …
Analysis of the effects of finite element type within a 3D biomechanical model of a human optic nerve head and posterior pole
Background and objective Biomechanical stresses and strains can be simulated in the optic
nerve head (ONH) using the finite element (FE) method, and various element types have …
nerve head (ONH) using the finite element (FE) method, and various element types have …
[HTML][HTML] A Gaussian process approach for rapid evaluation of skin tension
Skin tension plays a pivotal role in clinical settings, it affects scarring, wound healing and
skin necrosis. Despite its importance, there is no widely accepted method for assessing in …
skin necrosis. Despite its importance, there is no widely accepted method for assessing in …
Segmental biomechanics of the normal and glaucomatous human aqueous outflow pathway
The conventional aqueous outflow pathway, encompassing the trabecular meshwork (TM),
juxtacanalicular connective tissue (JCT), and inner wall endothelium of Schlemm's canal …
juxtacanalicular connective tissue (JCT), and inner wall endothelium of Schlemm's canal …
A machine learning approach to predict in vivo skin growth
Since their invention, tissue expanders, which are designed to trigger additional skin growth,
have revolutionised many reconstructive surgeries. Currently, however, the sole quantitative …
have revolutionised many reconstructive surgeries. Currently, however, the sole quantitative …
A mesh-free approach to incorporate complex anisotropic and heterogeneous material properties into eye-specific finite element models
R Grytz, K Krishnan, R Whitley, V Libertiaux… - Computer methods in …, 2020 - Elsevier
Commercial finite element modeling packages do not have the tools necessary to effectively
incorporate the complex anisotropic and heterogeneous material properties typical of the …
incorporate the complex anisotropic and heterogeneous material properties typical of the …
Modeling the biomechanics of the conventional aqueous outflow pathway microstructure in the human eye
Background and objective Intraocular pressure (IOP) is determined by aqueous humor
outflow resistance, which is a function of the combined resistance of Schlemm's canal (SC) …
outflow resistance, which is a function of the combined resistance of Schlemm's canal (SC) …