ACE2 and Mpro in the pathology of SARS-CoV-2 show great potential in developing COVID-
19 drugs as therapeutic targets, due to their roles as the “gate” of viral entry and viral …

Alpha mangostin (AM), the main xanthone derivative contained in mangosteen pericarp
(Garcinia mangostana/GM), has many pharmacological activities such as antioxidant …

The current treatments for wound healing still exhibit drawbacks due to limited availability at
the action sites, susceptibility to degradation, and immediate drug release, all of which are …

α-Mangostin (a xanthone derivative found in the pericarp of Garcinia mangostana L.) and
propolis extract (which is rich in flavonoids and phenols) are known for their antioxidant …

Nanoparticle systems integrating alginate and chitosan emerge as a promising avenue to
tackle challenges in leveraging the potency of pharmacological active agents. Owing to their …

In recent years, a cancer research trend has shifted towards identifying novel therapeutic
compounds from natural assets for the management of cancer. In this study, we aimed to …

Plants provide compounds that can be used to treat diseases, and in silico methods help to
expedite drug discovery while reducing costs. This study explored the phytochemical profile …

Currently, retinoids are known for their abundant benefits to skin health, ranging from
reducing signs of aging and decreasing hyperpigmentation to treating acne. However, it …

In Indonesia, plants have been indigenously used to treat various diseases and as
cosmetics. It is always challenging to explore the molecular interactions of phenolic …

Abstract Introduction: Costus cuspidatus and Costus subsessilis have shown cytotoxic
effects in HL60, Jurkat, and THP-1 cells. This study aimed to evaluate the cytotoxicity and …