Epstein–Barr virus epithelial cancers—A comprehensive understanding to drive novel therapies

S Han, JK Tay, CJL Loh, AJM Chu, JPS Yeong… - Frontiers in …, 2021 - frontiersin.org
Epstein–Barr virus (EBV) is a ubiquitous oncovirus associated with specific epithelial and
lymphoid cancers. Among the epithelial cancers, nasopharyngeal carcinoma (NPC) …

Recurrent/metastatic nasopharyngeal carcinoma treatment from present to future: where are we and where are we heading?

JJ Juarez-Vignon Whaley, M Afkhami… - … treatment options in …, 2023 - Springer
Opinion statement Nasopharyngeal carcinoma (NPC) is distinct in its anatomic location and
biology from other epithelial head and neck cancer (HNC). There are 3 WHO subtypes …

Analysis of cells of epithelial, connective tissue and immune differentiation in HPV-positive-, HPV-negative oropharyngeal carcinoma and normal oropharyngeal tissue …

AI Giotakis, A Runge, J Dudas, R Glueckert, T Gottfried… - BMC cancer, 2023 - Springer
Background Epithelial, connective tissue and immune cells contribute in various ways to the
pathophysiology of HPV positive (HPV+) and HPV negative (HPV-) oropharyngeal …

Recent advances in cardiovascular diseases research using animal models and PET radioisotope tracers

W Wargocka-Matuszewska, W Uhrynowski… - International Journal of …, 2022 - mdpi.com
Cardiovascular diseases (CVD) is a collective term describing a range of conditions that
affect the heart and blood vessels. Due to the varied nature of the disorders, distinguishing …

Heterogeneity of SSTR2 expression assessed by 68Ga-DOTATOC PET/CT using coefficient of variation in patients with neuroendocrine tumors

R Fonti, M Panico, S Pellegrino… - Journal of Nuclear …, 2022 - Soc Nuclear Med
High levels of somatostatin receptor subtype 2 (SSTR2) are a prerequisite for therapy with
unlabeled or labeled somatostatin analogs. However, it is still unclear how the heterogeneity …

Pathogenesis and therapeutic implications of EBV-associated epithelial cancers

YH Low, CJL Loh, DYY Peh, AJM Chu, S Han… - Frontiers in …, 2023 - frontiersin.org
Epstein-Barr virus (EBV), one of the most common human viruses, has been associated with
both lymphoid and epithelial cancers. Undifferentiated nasopharyngeal carcinoma (NPC) …

Advances in nuclear medicine-based molecular imaging in head and neck squamous cell carcinoma

D Li, X Li, J Zhao, F Tan - Journal of Translational Medicine, 2022 - Springer
Head and neck squamous cell carcinomas (HNSCCs) are often aggressive, making
advanced disease very difficult to treat using contemporary modalities, such as surgery …

SSTR2 in nasopharyngeal carcinoma: relationship with latent EBV infection and potential as a therapeutic target

O Emanuel, J Liu, VH Schartinger, WL Nei, YY Chan… - Cancers, 2021 - mdpi.com
Simple Summary Nasopharyngeal cancer (NPC) is a malignant epithelial tumor endemic to
parts of Asia and associated with infection by the Epstein–Barr virus (EBV) in these regions …

Immunological role and prognostic value of somatostatin receptor family members in colon adenocarcinoma

X Yu, X Yang, H Nie, W Jiang, X He… - Frontiers in Pharmacology, 2023 - frontiersin.org
Colon adenocarcinoma (COAD) is among the most prevalent cancers worldwide, ranking as
the third most prevalent malignancy in incidence and mortality. The somatostatin receptor …

Design, Preclinical Evaluation, and Clinical Translation of 68Ga-FAPI-LM3, a Heterobivalent Molecule for PET Imaging of Nasopharyngeal Carcinoma

L Zhao, Y Pang, J Fang, J Chen, Y Zhou… - Journal of Nuclear …, 2024 - Soc Nuclear Med
Extensive research has been conducted on radiolabeled fibroblast activation protein (FAP)
inhibitors (FAPIs) and p-Cl-Phe-cyclo (d-Cys-Tyr-d-4-amino-Phe (carbamoyl)-Lys-Thr-Cys) d …