The centenary of insulin discovery represents an important opportunity to transform diabetes
from a fatal diagnosis into a medically manageable chronic condition. Insulin is a key …

A sedentary lifestyle has been linked to a number of metabolic disorders that have been
associated with sub-optimal mitochondrial characteristics and an increased risk of …

Exercise training benefits many organ systems and offers protection against metabolic
disorders such as obesity and diabetes. Using the recently identified isoform of PGC1-α …

Aims We investigated whether sprint interval training (SIT) was a time-efficient exercise
strategy to improve insulin sensitivity and other indices of cardiometabolic health to the …

Endurance exercise-mediated multisystemic adaptations are known to mitigate metabolism-
related disorders such as obesity and type 2 diabetes mellitus (T2DM). However, the …

The aim of this study was to objectively quantify ratings of perceived enjoyment using the
Physical Activity Enjoyment Scale following high-intensity interval running versus moderate …

High‐intensity interval training (HIT) induces skeletal muscle metabolic and performance
adaptations that resemble traditional endurance training despite a low total exercise volume …

The benefits of endurance exercise on general health make it desirable to identify orally
active agents that would mimic or potentiate the effects of exercise to treat metabolic …

Conclusions: INT for 12 wk is an effective training stimulus for improvement of
cardiorespiratory fitness and glucose tolerance, but in relation to the treatment of …

Methods Seven sedentary but otherwise healthy individuals (three women) with a mean±SD
age, body mass index, and peak oxygen uptake (VO (2peak)) of 45±5 yr, 27±5 kg· m (-2) …