Colon cancer is the third most common cancer worldwide. Most colorectal cancer
occurrences are sporadic, not related to genetic predisposition or family history; however, 20 …

Gastroenteropancreatic (GEP) neuroendocrine neoplasms (NENs) are heterogeneous
regarding site of origin, biological behavior, and malignant potential. There has been a rapid …

The classification of neuroendocrine neoplasms (NENs) differs between organ systems and
currently causes considerable confusion. A uniform classification framework for NENs at any …

This ENETS guidance paper, developed by a multidisciplinary working group, provides up‐
to‐date and practical advice on the diagnosis and management of digestive neuroendocrine …

Gastroenteropancreatic (GEP) neuroendocrine neoplasm (NEN) that consists of
neuroendocrine tumor and neuroendocrine carcinoma (NEC) is a lethal but under …

This review is based on a presentation given at the Hans Popper Hepatopathology Society
companion meeting at the 2019 United States and Canadian Academy of Pathology Annual …

Mixed neuroendocrine non-neuroendocrine neoplasms (MiNENs) represent a rare
diagnosis of the gastro-entero-pancreatic tract. Evidence from the current literature …

Lynch syndrome is caused by germline mutations of DNA mismatch repair (MMR) genes.
MMR deficiency has long been regarded as a secondary event in the pathogenesis of Lynch …

Purpose: GEP-NENs are rare malignancies with increasing incidence. Their molecular
characteristics are still undefined. We explored the underlying biology of GEP-NENs and the …

Immunohistochemistry represents an indispensable complement to an epidemiology and
morphology-driven approach to tumor diagnosis and site of origin assignment. This review …