Health Effects of Ionizing Radiation on the Human Body

J Talapko, D Talapko, D Katalinić, I Kotris, I Erić… - Medicina, 2024 - mdpi.com
Radioactivity is a process in which the nuclei of unstable atoms spontaneously decay,
producing other nuclei and releasing energy in the form of ionizing radiation in the form of …

Cell Therapies for Acute Radiation Syndrome

BA Christy, MC Herzig, X Wu… - International journal of …, 2024 - mdpi.com
The risks of severe ionizing radiation exposure are increasing due to the involvement of
nuclear powers in combat operations, the increasing use of nuclear power, and the …

A data mining approach to identify key radioresponsive genes in mouse model of radiation-induced intestinal injury

S Sharma, A Rehan, A Dutta - Biomarkers, 2024 - Taylor & Francis
Background Radiation-mediated GI injury (RIGI) is observed in humans either due to
accidental or intentional exposures. This can only be managed with supporting care and no …

Uncovering the potential of Fatty Acid Binding Proteins for predicting radiation-induced gastrointestinal injury

S Sharma, A Rehan, S Kumar… - Chemical Biology …, 2025 - pubs.thesciencein.org
Gastrointestine (GI) depression is a severe complication identified in individuals after
intentional or unintentional radiation exposure. Early detection of radiation-induced GI injury …

Effects of combined ciprofloxacin and Neulasta therapy on intestinal pathology and gut microbiota after high-dose irradiation in mice

TS Horseman, AM Frank, G Cannon, M Zhai… - Frontiers in Public …, 2024 - frontiersin.org
Introduction Treatments that currently exist in the strategic national stockpile for acute
radiation syndrome (ARS) focus on the hematopoietic subsyndrome, with no treatments on …

Radiation Research Society Journal-based Historical Review of the Use of Biomarkers for Radiation Dose and Injury Assessment: Acute Health Effects Predictions

WF Blakely, M Port, P Ostheim… - Radiation …, 2024 - meridian.allenpress.com
A multiple-parameter based approach using radiation-induced clinical signs and symptoms,
hematology changes, cytogenetic chromosomal aberrations, and molecular biomarkers …

Mitigating the Effects of 1-Palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol on Gastrointestinal Acute Radiation Syndrome after Total-Body Irradiation in Mice

J Jeong, S Sun, YJ Kim, KY Sohn… - Radiation …, 2024 - meridian.allenpress.com
Total-body irradiation (TBI) with gamma rays can damage organisms in various unexpected
ways and trigger several organ dysfunction syndromes, such as acute radiation syndrome …

Natural-history Characterization of a Murine Partial-body Irradiation Model System: Establishment of a Multiple-Parameter Based GI-ARS Severity-Scoring System

DL Bolduc, LH Cary, JG Kiang, L Kurada… - Radiation …, 2024 - meridian.allenpress.com
The purpose of this investigation was to characterize the natural history of a murine total-
abdominal-irradiation exposure model to measure gastrointestinal acute radiation injury …

Histone deacetylase inhibitor, Trichostatin A mitigates ionizing radiation induced redox imbalance by regulating NRF2/GPX4/PINK1/PARKIN signaling in mice …

A Dahiya, S Sharma, PK Agrawala, A Dutta - Molecular Biology Reports, 2024 - Springer
Background Gastrointestinal-acute radiation syndrome (GI-ARS) caused by moderate to
high doses of ionizing radiation exposure contribute to early death in humans. GI injury is …

Trichostatin A mitigates acute and late effects of radiation in intestine by regulation of DNA damage repair and Wnt/TGFβ/Smad signaling

A Dahiya, A Rehan, P K. Agrawala… - International Journal of …, 2024 - Taylor & Francis
Purpose Radiation accidents and misuse of nuclear weapons elevate the risk of
development of acute life-threatening injuries as well as their late effects are noted in …