Mesenchymal stem cells (MSCs) are known as promising sources for cancer therapy and
can be utilized as vehicles in cancer gene therapy. MSC-derived exosomes are central …

Across the world, oral cancer is a prevalent tumor. Over the years, both its mortality and
incidence have grown. Oral cancer metastasis is a complex process involving cell invasion …

In our previous studies, enhancer of zeste homolog 2 (EZH2) has been proven to be a key
oncogenic driver in oral squamous cell carcinoma (OSCC). However, the regulatory …

MicroRNAs (miRNAs) are small noncoding RNAs that could regulate gene expressions
transcriptionally or post-transcriptionally through binding to 3'untranslated region (3'UTR) of …

CXC chemokine receptor 7 (CXCR7) is a G-protein-coupled receptor that signals through
the β-arrestin pathway. Its ligands include interferon-inducible T cell α chemoattractant …

Oral cancer is a multifactorial pathology and is characterized by the lack of efficient treatment
and accurate diagnostic tools. This is mainly due the late diagnosis; therefore, reliable …

Purpose Human epidermal growth factor receptor 2 positive (HER2+) breast cancers
responding poorly to targeted therapy need improved treatment options. miR-101-5p has …

Whereas TNF-α can facilitate the metastasis of oral squamous cancer cells (OSCC), whether
it inhibits the metastasis is not clear so far. In this study, we demonstrated that high dose TNF …

Background Oral squamous cell carcinoma (OSCC) has the highest mortality rate among all
head and neck cancers and a relatively low five-year survival rate. Generally, the …

Head and neck squamous cell carcinoma (HNSCC) is a leading cause of cancer-related
death worldwide. Despite aggressive treatment approaches, the recurrence of HNSCC …