Successful pregnancy requires carefully-coordinated communications between the mother
and fetus. Immune cells and cytokine signaling pathways participate as mediators of these …

The impact of infections and inflammation during pregnancy on the developing fetal brain
remains incompletely defined, with important clinical and research gaps. Although the …

Preterm birth which occurs before 37 weeks gestation is one of the most common obstetrical
complication in humans. After many studies, it appears that “not one answer fits all” …

Autism spectrum disorder (ASD) is a neurodevelopmental condition of the central nervous
system (CNS) that presents with severe communication problems, impairment of social …

As Zika virus (ZIKV) emerges into Dengue virus (DENV)-endemic areas, cases of ZIKV
infection in DENV-immune pregnant women may rise. Here we show that prior DENV …

The intrauterine environment provides a key interface between the mother and the
developing fetus during pregnancy, and is a target for investigating mechanisms of fetal …

The interaction between the peripheral immune system and the brain is increasingly being
recognized as an important layer of neuroimmune regulation and plays vital roles in brain …

Problem Autism spectrum disorder (ASD) is one of the most commonly diagnosed
neurodevelopmental disorders in the United States. While ASD can be significantly …

Background Intra-amniotic infection or inflammation is common in early preterm birth and
associated with substantial neonatal lung morbidity owing to fetal exposure to …

Zika virus (ZIKV) infection during pregnancy causes significant adverse sequelae in the
developing fetus, and results in long-term structural and neurologic defects. Most preventive …