Functions of interoception: From energy regulation to experience of the self
We review recent work on the functions of interoceptive processing, by which the nervous
system anticipates, senses, and integrates signals originating from the body. We focus on …
system anticipates, senses, and integrates signals originating from the body. We focus on …
Assessing neurogenic lower urinary tract dysfunction after spinal cord injury: Animal models in preclinical neuro-urology research
Neurogenic bladder dysfunction is a condition that affects both bladder storage and voiding
function and remains one of the leading causes of morbidity after spinal cord injury (SCI) …
function and remains one of the leading causes of morbidity after spinal cord injury (SCI) …
The NLRP3 inflammasome mediates inflammation produced by bladder outlet obstruction
FM Hughes Jr, HM Hill, CM Wood, AT Edmondson… - The Journal of …, 2016 - Elsevier
Purpose While bladder outlet obstruction is well established to elicit an inflammatory
reaction in the bladder that leads to overactive bladder and fibrosis, little is known about the …
reaction in the bladder that leads to overactive bladder and fibrosis, little is known about the …
[HTML][HTML] Intravesical activation of the cation channel TRPV4 improves bladder function in a rat model for detrusor underactivity
Y Deruyver, E Weyne, K Dewulf, R Rietjens, S Pinto… - European Urology, 2018 - Elsevier
Background Improvement of bladder emptying by modulating afferent nerve activity is an
attractive therapeutic strategy for detrusor underactivity. Transient receptor potential vanilloid …
attractive therapeutic strategy for detrusor underactivity. Transient receptor potential vanilloid …
Benefits and limitations of animal models in partial bladder outlet obstruction for translational research
T Kitta, Y Kanno, H Chiba, M Higuchi… - … Journal of Urology, 2018 - Wiley Online Library
The functions of the lower urinary tract have been investigated for more than a century.
Lower urinary tract symptoms, such as incomplete bladder emptying, weak urine stream …
Lower urinary tract symptoms, such as incomplete bladder emptying, weak urine stream …
From the rodent spinal cord injury model to human application: promises and challenges
V Dietz, ME Schwab - Journal of neurotrauma, 2017 - liebertpub.com
Repair of the spinal cord and improvement of mobility after injury has been a matter of basic
and clinical research for several decades. A number of repair approaches were performed in …
and clinical research for several decades. A number of repair approaches were performed in …
Anti-Nogo-A antibodies as a potential causal therapy for lower urinary tract dysfunction after spinal cord injury
MP Schneider, AM Sartori, BV Ineichen… - Journal of …, 2019 - Soc Neuroscience
Loss of bladder control is common after spinal cord injury (SCI) and no causal therapies are
available. Here we investigated whether function-blocking antibodies against the nerve-fiber …
available. Here we investigated whether function-blocking antibodies against the nerve-fiber …
Early sacral neuromodulation ameliorates urinary bladder function and structure in complete spinal cord injury minipigs
EE Keller, I Patras, I Hutu, K Roider… - Neurourology and …, 2020 - Wiley Online Library
Aims To determine the effects of early sacral neuromodulation (SNM) and pudendal
neuromodulation (PNM) on lower urinary tract (LUT) function, minipigs with complete spinal …
neuromodulation (PNM) on lower urinary tract (LUT) function, minipigs with complete spinal …
Molecular mechanism operating in animal models of neurogenic detrusor overactivity: A systematic review focusing on bladder dysfunction of neurogenic origin
A Ferreira, D Nascimento, CD Cruz - International Journal of Molecular …, 2023 - mdpi.com
Neurogenic detrusor overactivity (NDO) is a severe lower urinary tract disorder,
characterized by urinary urgency, retention, and incontinence, as a result of a neurologic …
characterized by urinary urgency, retention, and incontinence, as a result of a neurologic …
[HTML][HTML] The NACHT, LRR and PYD domains-containing protein 3 (NLRP3) inflammasome mediates inflammation and voiding dysfunction in a lipopolysaccharide …
FM Hughes Jr, JG Kennis, MN Youssef… - Journal of clinical & …, 2016 - ncbi.nlm.nih.gov
Objective NOD-like receptors (NLRs) sense sterile and non-sterile signals and form
inflammasomes which trigger an inflammatory response through the activation of caspase-1 …
inflammasomes which trigger an inflammatory response through the activation of caspase-1 …